Evidence map›Paper›PMID 15608258›Full record

ArticleNucleic acids research2005

T1DBase, a community web-based resource for type 1 diabetes research.

Luc J Smink, Erin M Helton, Barry C Healy, Christopher C Cavnor, Alex C Lam, Daisy Flamez, Oliver S Burren, Yang Wang, Geoffrey E Dolman, David B Burdick and 11 more

Open access · hybridAbstract read
In one paragraph

Article in Nucleic acids research, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
6.0field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 52 citations in OpenAlex.

  1. Risk variants disrupting enhancers of TProceedings of the National Academy of Sciences of the United States of America · 2019
    Trial
  2. Article
  3. DiabetesOmic: A comprehensive multi-omics diabetes database.Computational and structural biotechnology journal · 2025
    Article
  4. On building a diabetes centric knowledge base via mining the web.BMC medical informatics and decision making · 2019
    Article
  5. Review
  6. The circadian gene Arntl2 on distal mouse chromosome 6 controls thymocyte apoptosis.Mammalian genome : official journal of the International Mammalian Genome Society · 2017
    Article
  7. Article
  8. Fine mapping of type 1 diabetes regions Idd9.1 and Idd9.2 reveals genetic complexity.Mammalian genome : official journal of the International Mammalian Genome Society · 2013
    Article
  9. Article
  10. Article
  11. Article
  12. Evidence that Cd101 is an autoimmune diabetes gene in nonobese diabetic mice.Journal of immunology (Baltimore, Md. : 1950) · 2011
    Article
  13. Article
  14. EuroDia: a beta-cell gene expression resource.Database : the journal of biological databases and curation · 2010
    Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors at 1 institution in 1 country.

Luc J SminkJuvenile Diabetes Research Foundation/Wellcome Trust Diabetes and Inflammation Laboratory, Cambridge Institute for Medical Research, University of Cambridge, Wellcome Trust/MRC Building, Cambridge CB2 2XY, UK. Luc.Smink@cimr.cam.ac.uk
Erin M Helton
Barry C Healy
Christopher C Cavnor
Alex C Lam
Daisy Flamez
Oliver S Burren
Yang Wang
Geoffrey E Dolman
David B Burdick
Vincent H Everett
Gustavo Glusman
Davide Laneri
Lee Rowen
Helen Schuilenburg
Neil M Walker
Josyf Mychaleckyj
Linda S Wicker
Decio L Eizirik
John A Todd
Nathan Goodman
University of Cambridge · GB

Funding

Wellcome Trust
6 · The paper itself

Abstract

T1DBase (http://T1DBase.org) is a public website and database that supports the type 1 diabetes (T1D) research community. The site is currently focused on the molecular genetics and biology of T1D susceptibility and pathogenesis. It includes the following datasets: annotated genome sequence for human, rat and mouse; information on genetically identified T1D susceptibility regions in human, rat and mouse, and genetic linkage and association studies pertaining to T1D; descriptions of NOD mouse congenic strains; the Beta Cell Gene Expression Bank, which reports expression levels of genes in beta cells under various conditions, and annotations of gene function in beta cells; data on gene expression in a variety of tissues and organs; and biological pathways from KEGG and BioCarta. Tools on the site include the GBrowse genome browser, site-wide context dependent search, Connect-the-Dots for connecting gene and other identifiers from multiple data sources, Cytoscape for visualizing and analyzing biological networks, and the GESTALT workbench for genome annotation. All data are open access and all software is open source.

Indexed as

Databases, GeneticAnimalsBiomedical ResearchDatabase Management SystemsDiabetes Mellitus, Type 1Disease Models, AnimalGene ExpressionGenetic Predisposition to DiseaseGenomicsHumansInternetIslets of LangerhansMiceRatsUser-Computer Interface

Identifiers

PMID15608258
PMCPMC540049
OpenAlexW2125104861

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.