ArticleNucleic acids research2005
GenDiS: Genomic Distribution of protein structural domain Superfamilies.
Article in Nucleic acids research, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed.
- GenDiS3 database: census on the prevalence of protein domain superfamilies of known structure in the entire sequence database.Database : the journal of biological databases and curation · 2025Article
- Improved performance of sequence search approaches in remote homology detection.F1000Research · 2013Article
- Genome-wide survey of prokaryotic serine proteases: analysis of distribution and domain architectures of five serine protease families in prokaryotes.BMC genomics · 2008Article
- CUSP: an algorithm to distinguish structurally conserved and unconserved regions in protein domain alignments and its application in the study of large length variations.BMC structural biology · 2008Article
- A machine learning approach for the identification of odorant binding proteins from sequence-derived properties.BMC bioinformatics · 2007Article
- DIAL: a web-based server for the automatic identification of structural domains in proteins.Nucleic acids research · 2005Article
- Peptides encoded by noncoding genes: challenges and perspectives.Signal transduction and targeted therapyReview
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Authors and funding
3 authors.
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Abstract
Several proteins that have substantially diverged during evolution retain similar three-dimensional structures and biological function inspite of poor sequence identity. The database on Genomic Distribution of protein structural domain Superfamilies (GenDiS) provides record for the distribution of 4001 protein domains organized as 1194 structural superfamilies across 18,997 genomes at various levels of hierarchy in taxonomy. GenDiS database provides a survey of protein domains enlisted in sequence databases employing a 3-fold sequence search approach. Lineage-specific literature is obtained from the taxonomy database for individual protein members to provide a platform for performing genomic and phyletic studies across organisms. The database documents residual properties and provides alignments for the various superfamily members in genomes, offering insights into the rational design of experiments and for the better understanding of a superfamily. GenDiS database can be accessed at http://www.ncbs.res.in/~faculty/mini/gendis/home.html.
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