ReviewClinical and experimental immunology2005
Immunosuppression: towards a logical approach in liver transplantation.
Review in Clinical and experimental immunology, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
16 citing papers in PubMed.
- Innovative strategies in bile duct repair: Assessing efficacy and safety across varied graft techniques - A systematic review.Surgery open science · 2025Review
- Review
- Pharmacodynamic Drug-Drug Interaction on Human Peripheral Blood Mononuclear Cells Between Everolimus and Tacrolimus at the Therapeutic Concentration Range in Renal Transplantation.Annals of transplantation · 2021Article
- Extrahepatic bile duct reconstruction in pigs with heterogenous animal-derived artificial bile ducts: A preliminary experience.World journal of gastroenterology · 2020Article
- Induction Phase of Spontaneous Liver Transplant Tolerance.Frontiers in immunology · 2020Review
- Toxicity and in vivo release profile of sirolimus from implants into the vitreous of rabbits' eyes.Documenta ophthalmologica. Advances in ophthalmology · 2019Article
- Interaction of immunosuppressants with HCV antivirals daclatasvir and asunaprevir: combined effects with mycophenolic acid.World journal of transplantation · 2018Article
- Intra-individual variability of mycophenolic acid concentration according to renal function in liver transplant recipients receiving mycophenolate monotherapy.Annals of hepato-biliary-pancreatic surgery · 2017Article
- Change of strategies and future perspectives against hepatitis B virus recurrence after liver transplantation.World journal of gastroenterology · 2015Review
- Epithelial to mesenchymal transition in the liver field: the double face of Everolimus in vitro.BMC gastroenterology · 2015Article
- mTOR signaling in liver regeneration: Rapamycin combined with growth factor treatment.World journal of transplantation · 2013Article
- New developments in transplant-acquired allergies.World journal of transplantation · 2013Article
- An immune function assay predicts post-transplant recurrence in patients with hepatocellular carcinoma.Journal of cancer research and clinical oncology · 2011Article
- Strategies to modulate immune responses: a new frontier for gene therapy.Molecular therapy : the journal of the American Society of Gene Therapy · 2009Review
- Liver cirrhosis.Lancet (London, England) · 2008Review
- Critical care issues in adult liver transplantation.Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care MedicineArticle
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Over the last two decades there has been a significant increase in the number and types of immunosuppressive agents that have been available to clinicians. The protocols for immunosuppression used in liver transplantation have been derived historically from those in renal transplantation. During the last decade there has been a shift in the use of immunosuppression, with the introduction of interleukin (IL)-2 receptor antagonists in place of anti-lymphocyte preparations, substitution of tacrolimus for cyclosporin and mycophenolate for azathioprine. The use of corticosteroids has been reduced. For a variety of reasons, these changes have not always been made on the basis of properly randomized studies. The place of newer agents, such as sirolimus and leflunomide derivatives and of the microbiological agents, is unclear. In this review, we outline briefly the mechanism of action of drugs and suggest possible approaches to the management of the liver allograft recipient, suggesting how treatment could be adjusted according to the indication for transplantation as well as the individual's comorbidities.
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