Evidence map›Paper›PMID 15605286›Full record

ArticleDer Anaesthesist2005

Employing vasopressin as an adjunct vasopressor in uncontrolled traumatic hemorrhagic shock. Three cases and a brief analysis of the literature.

A C Krismer, V Wenzel, W G Voelckel, P Innerhofer, K H Stadlbauer, T Haas, M Pavlic, H J Sparr, K H Lindner, A Koenigsrainer

Registry-linked trialAbstract readCase Reports
PubMed Publisher
In one paragraph

Article in Der Anaesthesist, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00379522 (A Multicenter, Randomized, Controlled Trial Assessing Arginine Vasopressin Versus Saline Placebo in Refractory Traumatic Hemorrhagic Shock Patients), which is not on this map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
7.4field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT00379522 phase2 / phase3completednot on this mapstarted 2010, after this paper: background citation

A Multicenter, Randomized, Controlled Trial Assessing Arginine Vasopressin Versus Saline Placebo in Refractory Traumatic Hemorrhagic Shock Patients (VITRIS-study)

TypeinterventionalSponsorVolker WenzelRan2010 to 2014Enrolled64ConditionsShock, Hypovolemia, Hemorrhagic ShockArmsVasopressin, Saline placebo
3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 76 citations in OpenAlex.

  1. Trial
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  4. Article
  5. Role of vasopressin in current anesthetic practice.Korean journal of anesthesiology · 2017
    Review
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  7. Review
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  17. Review
  18. [Vasopressin].Der Anaesthesist · 2005
    Article
  19. Vasopressors: Do they have any role in hemorrhagic shock?Journal of anaesthesiology, clinical pharmacology
    Review
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

A C KrismerDepartment of Anesthesiology and Critical Care Medicine, Medical University, Innsbruck, Austria. anette.krismer@uibk.ac.at
V Wenzel
W G Voelckel
P Innerhofer
K H Stadlbauer
T Haas
M Pavlic
H J Sparr
K H Lindner
A Koenigsrainer
Innsbruck Medical University · AT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Resuscitation of patients in hemorrhagic shock remains one of the most challenging aspects of trauma care. We showed in experimental studies that vasopressin, but not fluid resuscitation, enabled short-term and long-term survival in a porcine model of uncontrolled hemorrhagic shock after penetrating liver trauma. In this case report, we present two cases with temporarily successful cardiopulmonary resuscitation (CPR) using vasopressin and catecholamines in uncontrolled hemorrhagic shock with subsequent cardiac arrest that was refractory to catecholamines and fluid replacement. In a third patient, an infusion of vasopressin was started before cardiac arrest occurred; in this case, we were able to stabilize blood pressure thus allowing further therapy. The patient underwent multiple surgical procedures, developed multi-organ failure, but was finally discharged from the critical care unit without neurological damage.

Indexed as

Abdominal InjuriesAccidental FallsAccidents, TrafficAdultAgedCardiopulmonary ResuscitationFemaleHeart ArrestHumansMaleMultiple Organ FailureShock, HemorrhagicVasoconstrictor AgentsVasopressinsWounds and InjuriesWounds, StabVasoconstrictor AgentsVasopressins

Identifiers

PMID15605286
OpenAlexW1503271965

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.