ArticleProceedings of the National Academy of Sciences of the United States of America2004
Genomic dissection of the cell-type-specification circuit in Saccharomyces cerevisiae.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 62 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
62 citing papers in PubMed.
- Cell-internal autocrine receptor inactivation supports maintenance of mating-type identity in yeast.Science advances · 2026Article
- Genetic and environmental control of parasexual reproduction in the pathogenicMicrobiology and molecular biology reviews : MMBR · 2025Review
- Multiple aspects of amyloid dynamicsFrontiers in molecular neuroscience · 2024Article
- Ploidy evolution in a wild yeast is linked to an interaction between cell type and metabolism.PLoS biology · 2023Article
- Evolution of a new form of haploid-specific gene regulation appearing in a limited clade of ascomycete yeast species.Genetics · 2023Article
- Haploinsufficiency of the sex-determining genes atiScience · 2022Article
- TheFrontiers in fungal biology · 2022Article
- Genetic analysis argues for a coactivator function for the Saccharomyces cerevisiae Tup1 corepressor.Genetics · 2021Article
- Post-Transcriptional Control of Mating-Type Gene Expression during Gametogenesis inBiomolecules · 2021Article
- The master regulator MAT1-1-1 of fungal mating binds to its targets via a conserved motif in the human pathogen Aspergillus fumigatus.G3 (Bethesda, Md.) · 2021Article
- Saline stress affects the pH-dependent regulation of the transcription factor PacC in the dermatophyte Trichophyton interdigitale.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2020Article
- Current Perspectives on Uniparental Mitochondrial Inheritance inPathogens (Basel, Switzerland) · 2020Review
- Review
- Amn1 governs post-mitotic cell separation in Saccharomyces cerevisiae.PLoS genetics · 2018Article
- Tight Regulation of Srs2 Helicase Activity Is Crucial for Proper Functioning of DNA Repair Mechanisms.G3 (Bethesda, Md.) · 2018Article
- Flip/flop mating-type switching in the methylotrophic yeast Ogataea polymorpha is regulated by an Efg1-Rme1-Ste12 pathway.PLoS genetics · 2017Article
- Sex and the Imperfect Fungi.Microbiology spectrum · 2017Review
- An Evolutionary Perspective on Yeast Mating-Type Switching.Genetics · 2017Review
- Polymorphisms in the yeast galactose sensor underlie a natural continuum of nutrient-decision phenotypes.PLoS genetics · 2017Article
- Gamete signalling underlies the evolution of mating types and their number.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2016Article
2 more citing papers are in PubMed but not listed here.
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Authors and funding
7 authors.
Funding
Abstract
The budding yeast Saccharomyces cerevisiae has three cell types (a cells, alpha cells, and a/alpha cells), each of which is specified by a unique combination of transcriptional regulators. This transcriptional circuit has served as an important model for understanding basic features of the combinatorial control of transcription and the specification of cell type. Here, using genome-wide chromatin immunoprecipitation, transcriptional profiling, and phylogenetic comparisons, we describe the complete cell-type-specification circuit for S. cerevisiae. We believe this work represents a complete description of cell-type specification in a eukaryote.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.