ReviewJournal of cellular and molecular medicine
Embryonic stem cells: a promising tool for cell replacement therapy.
Review in Journal of cellular and molecular medicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
34 citing papers in PubMed, 125 citations in OpenAlex.
- Article
- A Simplified and Effective Approach for the Isolation of Small Pluripotent Stem Cells Derived from Human Peripheral Blood.Biomedicines · 2023Article
- Merits and challenges of iPSC-derived organoids for clinical applications.Frontiers in cell and developmental biology · 2023Review
- SIRT1 Knockdown Enhances the Differentiation of Human Embryonic Stem Cells into Pancreatic β Cells.Development & reproduction · 2019Article
- Review
- HSP60 is required for stemness and proper differentiation of mouse embryonic stem cells.Experimental & molecular medicine · 2018Article
- Review
- Article
- Identification of embryonic stem cell activities in an embryonic cell line derived from marine medaka (Oryzias dancena).Fish physiology and biochemistry · 2015Article
- A Euploid Line of Human Embryonic Stem Cells Derived from a 43,XX,dup(9q),+12,-14,-15,-18,-21 Embryo.PloS one · 2015Article
- The role of tissue engineering and biomaterials in cardiac regenerative medicine.The Canadian journal of cardiology · 2014Review
- Preclinical stem cell therapy in Chagas Disease: Perspectives for future research.World journal of transplantation · 2013Review
- Somatic cell transformation into stem cell-like cells induced by different microenvironments.Organogenesis · 2013Review
- Injectable biodegradable hydrogels for embryonic stem cell transplantation: improved cardiac remodelling and function of myocardial infarction.Journal of cellular and molecular medicine · 2012Article
- Specific gene signatures and pathways in mesodermal cells and their derivatives derived from embryonic stem cells.Stem cell reviews and reports · 2012Review
- Functional characterization and gene expression profiling of α-smooth muscle actin expressing cardiomyocytes derived from murine induced pluripotent stem cells.Stem cell reviews and reports · 2012Article
- Minimally invasive cell-seeded biomaterial systems for injectable/epicardial implantation in ischemic heart disease.International journal of nanomedicine · 2012Review
- Expansion of human embryonic stem cells: a comparative study.Cell proliferation · 2011Article
- Stem cell therapy in heart diseases: a review of selected new perspectives, practical considerations and clinical applications.Current cardiology reviews · 2011Review
- Cell-based therapy for stroke.Journal of neural transmission (Vienna, Austria : 1996) · 2011Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Embryonic stem (ES) cells are revolutionizing the field of developmental biology as a potential tool to understand the molecular mechanisms occurring during the process of differentiation from the embryonic stage to the adult phenotype. ES cells harvested from the inner cell mass (ICM) of the early embryo can proliferate indefinitely in vitro while retaining the ability to differentiate into all somatic cells. Emerging results from mice models with ES cells are promising and raising tremendous hope among the scientific community for the ES-cell based cell replacement therapy (CRT) of various severe diseases. ES cells could potentially revolutionize medicine by providing an unlimited renewable source of cells capable of replacing or repairing tissues that have been damaged in almost all degenerative diseases such as diabetes, myocardial infarction and Parkinson's disease. This review updates the progress of ES cell research in CRT, discusses about the problems encountered in the practical utility of ES cells in CRT and evaluates how far this approach is successful experimentally.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.