ArticleHuman genomics2003
Reconstructing the genomic architecture of mammalian ancestors using multispecies comparative maps.
Article in Human genomics, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
14 citing papers in PubMed.
- Evolution of chromosomes and nuclear architectures of amniotes.Nature communications · 2025Article
- Reconstruction and evolutionary history of eutherian chromosomes.Proceedings of the National Academy of Sciences of the United States of America · 2017Article
- Divergent patterns of breakpoint reuse in Muroid rodents.Mammalian genome : official journal of the International Mammalian Genome Society · 2010Article
- Characterization and distribution of retrotransposons and simple sequence repeats in the bovine genome.Proceedings of the National Academy of Sciences of the United States of America · 2009Article
- Comparative genome mapping of the deer mouse (Peromyscus maniculatus) reveals greater similarity to rat (Rattus norvegicus) than to the lab mouse (Mus musculus).BMC evolutionary biology · 2008Article
- Gene-interleaving patterns of synteny in the Saccharomyces cerevisiae genome: are they proof of an ancient genome duplication event?Biology direct · 2007Article
- Gene order data from a model amphibian (Ambystoma): new perspectives on vertebrate genome structure and evolution.BMC genomics · 2006Article
- HLA-E, HLA-F, and HLA-G polymorphism: genomic sequence defines haplotype structure and variation spanning the nonclassical class I genes.Immunogenetics · 2006Article
- The convergence of cytogenetics and rearrangement-based models for ancestral genome reconstruction.Genome research · 2006Article
- High resolution physical map of porcine chromosome 7 QTL region and comparative mapping of this region among vertebrate genomes.BMC genomics · 2006Article
- Comparative architectures of mammalian and chicken genomes reveal highly variable rates of genomic rearrangements across different lineages.Genome research · 2005Article
- Sequence and comparative analysis of the chicken genome provide unique perspectives on vertebrate evolution.Nature · 2004Article
- A 1463 gene cattle-human comparative map with anchor points defined by human genome sequence coordinates.Genome research · 2004Article
- Reconstructing the genomic architecture of ancestral mammals: lessons from human, mouse, and rat genomes.Genome research · 2004Article
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
Rapidly developing comparative gene maps in selected mammal species are providing an opportunity to reconstruct the genomic architecture of mammalian ancestors and study rearrangements that transformed this ancestral genome into existing mammalian genomes. Here, the recently developed Multiple Genome Rearrangement (MGR) algorithm is applied to human, mouse, cat and cattle comparative maps (with 311-470 shared markers) to impute the ancestral mammalian genome. Reconstructed ancestors consist of 70-100 conserved segments shared across the genomes that have been exchanged by rearrangement events along the ordinal lineages leading to modern species genomes. Genomic distances between species, dominated by inversions (reversals) and translocations, are presented in a first multispecies attempt using ordered mapping data to reconstruct the evolutionary exchanges that preceded modern placental mammal genomes.
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