ArticleMammalian genome : official journal of the International Mammalian Genome Society2004
A physical map of large segments of pig chromosome 7q11-q14: comparative analysis with human chromosome 6p21.
Article in Mammalian genome : official journal of the International Mammalian Genome Society, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed, 24 citations in OpenAlex.
- Wild Boar (Pathogens (Basel, Switzerland) · 2022Article
- Localization, expression change in PRRSV infection and association analysis of the porcine TAP1 gene.International journal of biological sciences · 2012Article
- Molecular characterization, expression profile and association analysis with fat deposition traits of the porcine APOM gene.Molecular biology reports · 2010Article
- Haplotypes of the porcine peroxisome proliferator-activated receptor delta gene are associated with backfat thickness.BMC genetics · 2009Article
- A robust linkage map of the porcine autosomes based on gene-associated SNPs.BMC genomics · 2009Article
- Diversification of porcine MHC class II genes: evidence for selective advantage.Immunogenetics · 2009Article
- Duplication polymorphism at MHC class II DRB1 locus in the wild boar (Sus scrofa).Immunogenetics · 2009Article
- High resolution physical map of porcine chromosome 7 QTL region and comparative mapping of this region among vertebrate genomes.BMC genomics · 2006Article
- Comparative analysis of a BAC contig of porcine chromosome 13q31-q32 and human chromosome 3q21-q22.BMC genomics · 2005Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The aim of this study was to establish a porcine physical map along the chromosome SSC7q by construction of BAC contigs between microsatellites Sw1409 and S0102. The SLA class II contig, located on SSC7q, was lengthened. Four major BAC contigs and 10 short contigs span a region equivalent to 800 cR measured by IMpRH7000 mapping. The BAC contigs were initiated by PCR screening with primers derived from human orthologous segments, extended by chromosome walking, and controlled and oriented by RH mapping with the two available panels, IMpRH7000Rad and IMNpRH12000Rad. The location of 43 genes was revealed by sequenced segments, either from BAC ends or PCR products from BAC clones. The 220 BAC end sequences (BES) were also used to analyze the different marks of evolution. Comparative mapping analysis between pigs and humans demonstrated that the gene organization on HSA6p21 and on SSC7p11 and q11-q14 segments was conserved during evolution, with the exception of long fragments of HSA6p12 which shuffled and spliced the SLA extended class II region. Additional punctual variations (unique gene insertion/deletion) were observed, even within conserved segments, revealing the evolutionary complexity of this region. In addition, 18 new polymorphic microsatellites have been selected in order to cover the entire SSC7p11-q14 region.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.