ArticleMammalian genome : official journal of the International Mammalian Genome Society2004
Development of a highly fecund inbred strain of mice.
Article in Mammalian genome : official journal of the International Mammalian Genome Society, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed.
- Article
- Perivascular cells induce microglial phagocytic states and synaptic engulfment via SPP1 in mouse models of Alzheimer's disease.Nature neuroscience · 2023Article
- Genomic characterization of the world's longest selection experiment in mouse reveals the complexity of polygenic traits.BMC biology · 2022Article
- Unpredictable Effects of the Genetic Background of Transgenic Lines in Physiological Quantitative Traits.G3 (Bethesda, Md.) · 2019Article
- An integrative genomic analysis of the superior fecundity phenotype in QSi5 mice.Molecular biotechnology · 2013Article
- In silico QTL mapping of maternal nurturing ability with the mouse diversity panel.Physiological genomics · 2012Article
- Transcriptome analysis identifies pathways associated with enhanced maternal performance in QSi5 mice.BMC genomics · 2008Article
- Quantitative trait loci for steady-state platelet count in mice.Mammalian genome : official journal of the International Mammalian Genome Society · 2004Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A highly fecund inbred mouse line has been established from the Quackenbush Swiss (QS) outbred strain by full-sib inbreeding combined with selection for high number of pups born alive (NBA) and low interlitter interval (ILI). After more than 50 generations of inbreeding and selection, this line, named QSi5, has an NBA of 13.4 and an ILI of 29 days, averaged over the first four parities, and a total productivity of 50.7 NBA. With its exceptional reproductive performance, this line will be very useful in the creation of resources (including advanced intercross lines) for analysis of quantitative trait loci for a wide range of traits, and for the cost-effective creation of congenic lines.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.