Evidence map›Paper›PMID 15598839›Full record

ArticleBioinformatics (Oxford, England)2005

Visualizing information across multidimensional post-genomic structured and textual databases.

Ying Tao, Carol Friedman, Yves A Lussier

Abstract read
In one paragraph

Article in Bioinformatics (Oxford, England), 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Natural language processing in the molecular imaging domain.AMIA ... Annual Symposium proceedings. AMIA Symposium · 2005
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Ying TaoDepartment of Biomedical Informatics, Columbia University, 622 West 168th Street, Vanderbilt Clinic, 5th Floor, New York, NY 10032, USA.
Carol Friedman
Yves A Lussier

Funding

Treatments for Nipah Virus InfectionU54AI057159 · NIAID · HARVARD UNIVERSITY (MEDICAL SCHOOL) · PI HARRISON, STEPHEN COPLAN · 2003 to 2013
$113.7M
Capturing and linking genomic and clinical informationR01LM007659 · NLM · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI FRIEDMAN, CAROL · 2003 to 2006
$1.9M
Semantic Approaches to Phenotypic Databases AnalysesK22LM008308 · NLM · UNIVERSITY OF CHICAGO · PI LUSSIER, YVES A · 2004 to 2006
$468k
NIAID NIH HHS 1U54 AI 57159-01NIAID NIH HHS U54 AI057159NLM NIH HHS 1K22 LM008308-01NLM NIH HHS K22 LM008308NLM NIH HHS R01 LM007659NLM NIH HHS R01 LM007659-01
6 · The paper itself

Abstract

motivationVisualizing relationships among biological information to facilitate understanding is crucial to biological research during the post-genomic era. Although different systems have been developed to view gene-phenotype relationships for specific databases, very few have been designed specifically as a general flexible tool for visualizing multidimensional genotypic and phenotypic information together. Our goal is to develop a method for visualizing multidimensional genotypic and phenotypic information and a model that unifies different biological databases in order to present the integrated knowledge using a uniform interface.

resultsWe developed a novel, flexible and generalizable visualization tool, called PhenoGenesviewer (PGviewer), which in this paper was used to display gene-phenotype relationships from a human-curated database (OMIM) and from an automatic method using a Natural Language Processing tool called BioMedLEE. Data obtained from multiple databases were first integrated into a uniform structure and then organized by PGviewer. PGviewer provides a flexible query interface that allows dynamic selection and ordering of any desired dimension in the databases. Based on users' queries, results can be visualized using hierarchical expandable trees that present views specified by users according to their research interests. We believe that this method, which allows users to dynamically organize and visualize multiple dimensions, is a potentially powerful and promising tool that should substantially facilitate biological research. AVAILABILITY: PhenogenesViewer as well as its support and tutorial are available at http://www.dbmi.columbia.edu/pgviewer/ CONTACT: Lussier@dbmi.columbia.edu.

Indexed as

Database Management SystemsDatabases, BibliographicDatabases, GeneticModels, BiologicalNatural Language ProcessingUser-Computer InterfaceComputer GraphicsDocumentationGene Expression ProfilingGenomicsHumansInformation Storage and RetrievalPeriodicals as Topic

Identifiers

PMID15598839
PMCPMC2901923

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.