Evidence map›Paper›PMID 15598805›Full record

ArticleThe Plant cell2005

Class III homeodomain-leucine zipper gene family members have overlapping, antagonistic, and distinct roles in Arabidopsis development.

Michael J Prigge, Denichiro Otsuga, José M Alonso, Joseph R Ecker, Gary N Drews, Steven E Clark

Open access · bronzeAbstract read
In one paragraph

Article in The Plant cell, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 334 papers.

0numbers the graph read from it
0cells of the map it votes in
334citing papers in PubMed
35.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

334 citing papers in PubMed, 809 citations in OpenAlex.

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274 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Michael J PriggeDepartment of Molecular, Cellular and Developmental Biology, University of Michigan, An Arbor, Michigan 48109-1048, USA.
Denichiro Otsuga
José M Alonso
Joseph R Ecker
Gary N Drews
Steven E Clark
Salk Institute for Biological Studies · USUniversity of Michigan–Ann Arbor · USUniversity of Utah · US

Funding

FUNCTIONAL ANALYSIS OF THE ARABIDOPSIS CLV COMPLEXF32GM020900 · NIGMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI PRIGGE, MICHAEL J · 2001 to 2003
$127k
NIGMS NIH HHS F32 GM020900NIGMS NIH HHS GM20900
6 · The paper itself

Abstract

The Arabidopsis thaliana genome contains five class III homeodomain-leucine zipper genes. We have isolated loss-of-function alleles for each family member for use in genetic analysis. This gene family regulates apical embryo patterning, embryonic shoot meristem formation, organ polarity, vascular development, and meristem function. Genetic analyses revealed a complex pattern of overlapping functions, some of which are not readily inferred by phylogenetic relationships or by gene expression patterns. The PHABULOSA and PHAVOLUTA genes perform overlapping functions with REVOLUTA, whereas the PHABULOSA, PHAVOLUTA, and CORONA/ATHB15 genes perform overlapping functions distinct from REVOLUTA. Furthermore, ATHB8 and CORONA encode functions that are both antagonistic to those of REVOLUTA within certain tissues and overlapping with REVOLUTA in other tissues. Differences in expression patterns explain some of these genetic interactions, whereas other interactions are likely attributable to differences in protein function as indicated by cross-complementation studies.

Indexed as

ArabidopsisArabidopsis ProteinsGene Expression Regulation, PlantGenes, HomeoboxGenome, PlantHomeodomain ProteinsLeucine ZippersMolecular Sequence DataMultigene FamilyMutationPhylogenyPlant ShootsSeedsArabidopsis ProteinsHomeodomain Proteins

Identifiers

PMID15598805
PMCPMC544490
OpenAlexW2125503823

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.