ArticleBiophysical journal2005
Direct visualization of asymmetric behavior in supported lipid bilayers at the gel-fluid phase transition.
Article in Biophysical journal, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed.
- A Spectroelectrochemical Study of the Effect of Asymmetry on the Electrochemical Response of Lipid Bilayers.The journal of physical chemistry. B · 2026Article
- Melittin-Induced Structural Transformations in DMPG and DMPS Lipid Membranes: A Langmuir Monolayer and AFM Study.Molecules (Basel, Switzerland) · 2024Article
- Assessing the Quality of Solvent-Assisted Lipid Bilayers Formed at Different Phases and Aqueous Buffer Media: A QCM-D Study.Sensors (Basel, Switzerland) · 2024Article
- Structure and thermodynamics of supported lipid membranes on hydrophobic van der Waals surfaces.Soft matter · 2024Article
- Hybrid bilayer membranes as platforms for biomimicry and catalysis.Nature reviews. Chemistry · 2022Review
- Correlated diffusion in lipid bilayers.Proceedings of the National Academy of Sciences of the United States of America · 2021Article
- Article
- Effects of lipid membrane composition on the distribution of biocidal guanidine oligomer with solid supported lipid membranes.RSC advances · 2020Article
- Lipid Bilayer Thickness Measured by Quantitative DIC Reveals Phase Transitions and Effects of Substrate Hydrophilicity.Langmuir : the ACS journal of surfaces and colloids · 2019Article
- Phase behavior of supported lipid bilayers: A systematic study by coarse-grained molecular dynamics simulations.The Journal of chemical physics · 2017Article
- Cytoskeletal pinning controls phase separation in multicomponent lipid membranes.Biophysical journal · 2015Article
- Beyond Saffman-Delbruck approximation: a new regime for 2D diffusion of α-hemolysin complexes in supported lipid bilayer.The European physical journal. E, Soft matter · 2012Article
- Effect of physical parameters on the main phase transition of supported lipid bilayers.Biophysical journal · 2009Article
- Diffusion in supported lipid bilayers: influence of substrate and preparation technique on the internal dynamics.The European physical journal. E, Soft matter · 2009Article
- Structure and thermotropic phase behavior of fluorinated phospholipid bilayers: a combined attenuated total reflection FTIR spectroscopy and imaging ellipsometry study.The journal of physical chemistry. B · 2008Article
- Thermal response of Langmuir-Blodgett films of dipalmitoylphosphatidylcholine studied by atomic force microscopy and force spectroscopy.Biophysical journal · 2007Article
- Poly-L-lysine-induced morphology changes in mixed anionic/zwitterionic and neat zwitterionic-supported phospholipid bilayers.Biophysical journal · 2006Article
- Coexisting stripe- and patch-shaped domains in giant unilamellar vesicles.Biochemistry · 2006Article
- Structured water layers adjacent to biological membranes.Biophysical journal · 2006Article
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We utilize in situ, temperature-dependent atomic force microscopy to examine the gel-fluid phase transition behavior in supported phospholipid bilayers constructed from 1,2-dimyristoyl-sn-glycero-3-phosphocholine, 1,2-dipentadecanoyl-sn-glycero-3-phosphocholine, and 1,2-dipalmitoyl-sn-glycero-3-phosphocholine. The primary gel-fluid phase transition at T(m) occurs through development of anisotropic cracks in the gel phase, which develop into the fluid phase. At approximately 5 degrees C above T(m), atomic force microscopy studies reveal the presence of a secondary phase transition in all three bilayers studied. The secondary phase transition occurs as a consequence of decoupling between the two leaflets of the bilayer due to enhanced stabilization of the lower leaflet with either the support or the water entrained between the support and the bilayer. Addition of the transmembrane protein gramicidin A or construction of a highly defected gel phase results in elimination of this decoupling and removal of the secondary phase transition.
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