Evidence map›Paper›PMID 15592734›Full record

SynthesisJournal of neurology2004

Spontaneous regression of brain arteriovenous malformations--a clinical study and a systematic review of the literature.

Dennis R Buis, René van den Berg, Geert Lycklama, H Bart van der Worp, Clemens M F Dirven, W Peter Vandertop

Abstract readCase ReportsComparative StudySystematic Review
PubMed Publisher
In one paragraph

Synthesis in Journal of neurology, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it.

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  8. Review
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  15. Spontaneous closure of cerebral dural arteriovenous fistulas with direct cortical venous drainage. A case report.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2009
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Dennis R BuisDept. of Neurosurgery, VU University Medical Center, 2D 168, P. O. Box 7057, 1007, MB Amsterdam, The Netherlands. dr.buis@vumc.nl
René van den Berg
Geert Lycklama
H Bart van der Worp
Clemens M F Dirven
W Peter Vandertop

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objective and importanceComplete spontaneous obliteration of a brain arteriovenous malformation (AVM) is a rare event, with 67 angiographically proven cases in the world literature. We present a new case and a systematic literature review to determine possible mechanisms underlying this unusual phenomenon. CLINICAL PRESENTATION: One patient with a brain AVM was referred for radiosurgical treatment. Shortly before treatment however, complete spontaneous regression occurred. This patient had experienced a hemorrhage in the months before referral.

resultsWe found 38 articles in which 67 cases of complete and spontaneous regression of a brain AVM were presented. Male to female ratio was 1.2, with a mean age of 37 years (range 1-81). Regression occurred in 72% without new neurological events. Median size of the nidus was 2 cm (range 1-7). There was a single arterial feeder in 46 % and a single draining vein in 59%.

conclusionSpontaneous regression of a brain AVM is the result of multiple interacting factors. Intracranial hemorrhage and the presence of a single draining vein seem to play a major role in this process.

Indexed as

Intracranial Arteriovenous MalformationsCerebral AngiographyHumansMaleMiddle AgedRadiosurgeryRemission, Spontaneous

Identifiers

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.