ArticleThe Korean journal of parasitology2004
Organ-specific antigens of Clonorchis sinensis.
Article in The Korean journal of parasitology, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
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Who cites it
8 citing papers in PubMed, 18 citations in OpenAlex.
- Identification of Myoferlin, a Potential Serodiagnostic Antigen of Clonorchiasis,Frontiers in cellular and infection microbiology · 2021Article
- In vitro maintenance of Clonorchis sinensis adult worms.The Korean journal of parasitology · 2012Article
- Article
- Multiple recombinant antigens of Clonorchis sinensis for serodiagnosis of human clonorchiasis.Parasitology research · 2011Article
- Differential gene expression profiling in human cholangiocarcinoma cells treated with Clonorchis sinensis excretory-secretory products.Parasitology research · 2009Article
- Bile components and amino acids affect survival of the newly excysted juvenile Clonorchis sinensis in maintaining media.Parasitology research · 2008Article
- Molecular characterization and serodiagnosis analysis of a novel lysophospholipase from Clonorchis sinensis.Parasitology research · 2007Article
- Long-term storage of Clonorchis sinensis metacercariae in vitro.Parasitology research · 2006Article
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This study was carried out to find out specific proteins from different organs of Clonorchis sinensis. Crude extract, organ-specific and excretory-secretory (ES) proteins were analyzed by immunoblot with infected human sera. The bands of 7- and 17-kDa were main component of intestinal fluid and ES protein and commonly found in all organspecific proteins. The 17-kDa protein was observed from ES antigen, intestinal fluid, eggs and sperms, 26- and 28-kDa proteins were from the uterus, vitellaria, and ovary, and 34-, 37-, 43- and 50-kDa proteins were mainly from the testis and sperms. Serum of mice immunized with sperms reacted to the 50-kDa protein by immunoblotting and immunohistochemical staining showed a positive reaction at the seminal receptacle and seminiferous tubule. The present results show that the 7-kDa protein is a common antigen of every part or organ of C. sinensis, but different organs express their specific antigenic protein bands.
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Registered trials
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