Genotypes and phenotypes in Crohn's disease: do they help in clinical management?

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

21 citing papers in PubMed, 64 citations in OpenAlex.

1. Managing Crohn's Disease Postoperative Recurrence Beyond Prophylaxis: A Comprehensive Review with Meta-Analysis.Biomedicines · 2024
   Review
2. Management of Pelvic Pain in Patients with Crohn's Disease-Current Overview.Journal of clinical medicine · 2023
   Review
3. Crohn's Disease Obstructions.Clinics in colon and rectal surgery · 2021
   Review
4. Distinct clinical phenotypes for Crohn's disease derived from patient surveys.BMC gastroenterology · 2021
   Article
5. Anti-TNF Therapy in Crohn's Disease.International journal of molecular sciences · 2018
   Review
6. Nod2: A Critical Regulator of Ileal Microbiota and Crohn's Disease.Frontiers in immunology · 2016
   Review
7. NOD1 and NOD2: signaling, host defense, and inflammatory disease.Immunity · 2014
   Review
8. Antimicrobial peptides and gut microbiota in homeostasis and pathology.EMBO molecular medicine · 2013
   Review
9. Nod2: a key regulator linking microbiota to intestinal mucosal immunity.Journal of molecular medicine (Berlin, Germany) · 2012
   Review
10. Association of a functional variant in the Wnt co-receptor LRP6 with early onset ileal Crohn's disease.PLoS genetics · 2012
    Article
11. Perianal Crohn's disease: predictive factors and genotype-phenotype correlations.Digestive surgery · 2012
    Article
12. Animal models of IBD: linkage to human disease.Current opinion in pharmacology · 2010
    Review
13. Risk factors associated with progression to intestinal complications of Crohn's disease in a population-based cohort.Gastroenterology · 2010
    Article
14. Induction and rescue of Nod2-dependent Th1-driven granulomatous inflammation of the ileum.Proceedings of the National Academy of Sciences of the United States of America · 2010
    Article
15. Navigating the road to personalized medicine: can we believe?CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2010
    Article
16. Nod2 is required for the regulation of commensal microbiota in the intestine.Proceedings of the National Academy of Sciences of the United States of America · 2009
    Article
17. Phenotypic and genotypic characteristics of inflammatory bowel disease in French Canadians: comparison with a large North American repository.The American journal of gastroenterology · 2009
    Article
18. Disease behavior in children with Crohn's disease: the effect of disease duration, ethnicity, genotype, and phenotype.Digestive diseases and sciences · 2009
    Article
19. Genetic variants of Wnt transcription factor TCF-4 (TCF7L2) putative promoter region are associated with small intestinal Crohn's disease.PloS one · 2009
    Article
20. IBD5 is associated with an extensive complicated Crohn's disease feature: implications from genotype-phenotype analysis.Gut · 2007
    Article

Corrections and comments

• Erratum issued

Authors and funding

2 authors at 1 institution in 1 country.

Funding

No grant is acknowledged in the PubMed record.

Abstract

PubMed holds no abstract for this paper.

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