ArticleGenome research2005
Comparative architectures of mammalian and chicken genomes reveal highly variable rates of genomic rearrangements across different lineages.
Article in Genome research, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 75 papers.
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Who cites it
75 citing papers in PubMed, 161 citations in OpenAlex.
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- Reconstruction of avian ancestral karyotypes reveals differences in the evolutionary history of macro- and microchromosomes.Genome biology · 2018Article
- Whole Genome Sequencing,G3 (Bethesda, Md.) · 2018Article
- Reconstruction of ancestral chromosome architecture and gene repertoire reveals principles of genome evolution in a model yeast genus.Genome research · 2016Article
- Membrane-associated collagens with interrupted triple-helices (MACITs): evolution from a bilaterian common ancestor and functional conservation in C. elegans.BMC evolutionary biology · 2015Article
- The sea lamprey meiotic map improves resolution of ancient vertebrate genome duplications.Genome research · 2015Article
- Harnessing cross-species alignment to discover SNPs and generate a draft genome sequence of a bighorn sheep (Ovis canadensis).BMC genomics · 2015Article
- A high resolution map of mammalian X chromosome fragile regions assessed by large-scale comparative genomics.Mammalian genome : official journal of the International Mammalian Genome Society · 2014Article
- Tracing the evolution of amniote chromosomes.Chromosoma · 2014Review
- Robustness of birth-death and gain models for inferring evolutionary events.BMC genomics · 2014Article
- Twisted signatures of GC-biased gene conversion embedded in an evolutionary stable karyotype.Molecular biology and evolution · 2013Article
- Reference-assisted chromosome assembly.Proceedings of the National Academy of Sciences of the United States of America · 2013Article
- Heterogeneous tempo and mode of conserved noncoding sequence evolution among four mammalian orders.Genome biology and evolution · 2013Article
- Extensive conservation of ancient microsynteny across metazoans due to cis-regulatory constraints.Genome research · 2012Article
15 more citing papers are in PubMed but not listed here.
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Authors and funding
5 authors at 3 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Molecular evolution studies are usually based on the analysis of individual genes and thus reflect only small-range variations in genomic sequences. A complementary approach is to study the evolutionary history of rearrangements in entire genomes based on the analysis of gene orders. The progress in whole genome sequencing provides an unprecedented level of detailed sequence data to infer genome rearrangements through comparative approaches. The comparative analysis of recently sequenced rodent genomes with the human genome revealed evidence for a larger number of rearrangements than previously thought and led to the reconstruction of the putative genomic architecture of the murid rodent ancestor, while the architecture of the ancestral mammalian genome and the rate of rearrangements in the human lineage remained unknown. Sequencing the chicken genome provides an opportunity to reconstruct the architecture of the ancestral mammalian genome by using chicken as an outgroup. Our analysis reveals a very low rate of rearrangements and, in particular, interchromosomal rearrangements in chicken, in the early mammalian ancestor, or in both. The suggested number of interchromosomal rearrangements between the mammalian ancestor and chicken, during an estimated 500 million years of evolution, only slightly exceeds the number of interchromosomal rearrangements that happened in the mouse lineage, over the course of about 87 million years.
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