ArticleJournal of clinical microbiology2004
High prevalence of natural Chlamydophila species infection in calves.
Article in Journal of clinical microbiology, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
24 citing papers in PubMed, 81 citations in OpenAlex.
- Seroprevalence and Risk Factors ofAnimals : an open access journal from MDPI · 2023Article
- Article
- Comparative analysis of two genomes of Chlamydia pecorum isolates from an Alpine chamois and a water buffalo.BMC genomics · 2022Article
- Phylogenetic and molecular analysis based on genes 16S-rRNA, OMPA and POMP to identifyIranian journal of microbiology · 2021Article
- Seroprevalence of Seven Reproductive Diseases in Beef and Dairy Cows from Three Provinces in Indonesia.Veterinary medicine international · 2021Article
- Peptide ELISA and FRET-qPCR Identified a Significantly Higher Prevalence ofPathogens (Basel, Switzerland) · 2020Article
- Seroprevalence and associated risk factors for chlamydiosis, coxiellosis and brucellosis in sheep and goats in Borana pastoral area, southern Ethiopia.BMC veterinary research · 2020Article
- Sero-prevalence of chlamydiosis in cattle and selected wildlife species at a wildlife/livestock interface area of Zimbabwe.Tropical animal health and production · 2018Article
- Culture-independent genome sequencing of clinical samples reveals an unexpected heterogeneity of infections by Chlamydia pecorum.Journal of clinical microbiology · 2015Article
- Kinetics of Local and Systemic Leucocyte and Cytokine Reaction of Calves to Intrabronchial Infection with Chlamydia psittaci.PloS one · 2015Article
- Article
- Molecular and pathological insights into Chlamydia pecorum-associated sporadic bovine encephalomyelitis (SBE) in Western Australia.BMC veterinary research · 2014Article
- Seroprevalence of Chlamydophila abortus infection in yaks (Bos grunniens) in Qinghai, China.Tropical animal health and production · 2014Article
- Genome sequencing and comparative analysis of three Chlamydia pecorum strains associated with different pathogenic outcomes.BMC genomics · 2014Article
- Host adaptation of Chlamydia pecorum towards low virulence evident in co-evolution of the ompA, incA, and ORF663 Loci.PloS one · 2014Article
- Multilocus sequence analysis provides insights into molecular epidemiology of Chlamydia pecorum infections in Australian sheep, cattle, and koalas.Journal of clinical microbiology · 2013Article
- Article
- Asymptomatic endemic Chlamydia pecorum infections reduce growth rates in calves by up to 48 percent.PloS one · 2012Article
- A bovine model of respiratory Chlamydia psittaci infection: challenge dose titration.PloS one · 2012Article
- Simultaneous differential detection of Chlamydophila abortus, Chlamydophila pecorum and Coxiella burnetii from aborted ruminant's clinical samples using multiplex PCR.BMC microbiology · 2009Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We investigated the acquisition and prevalence of Chlamydophila sp. infection in calves. Specimens were collected at weekly intervals from birth to week 12 postpartum from 40 female Holstein calf-dam pairs in a dairy herd. Real-time PCR detected, quantified, and differentiated Chlamydophila 23S rRNA gene DNA from vaginal cytobrush swabs and milk samples. Chemiluminescence enzyme-linked immunosorbent assay with lysed Chlamydophila abortus or Chlamydophila pecorum elementary body antigens quantified antibodies against Chlamydophila spp. in sera. Chlamydophila sp. DNA was found in 61% of calves and 20% of dams in at least one positive quantitative PCR. In calves, clinically inapparent C. pecorum infection with low organism loads was fivefold more prevalent than C. abortus infection and was most frequently detected by vaginal swabs compared to rectal or nasal swabs. In dams, C. abortus dominated in milk and C. pecorum dominated in the vagina. The group size of calves correlated positively (P < 0.01) with Chlamydophila infection in quadratic, but not linear, regression. Thus, a doubling of the group size was associated with a fourfold increase in frequency and intensity of Chlamydophila infection. For groups of 14 or 28 calves, respectively, logistic regression predicted a 9 or 52% probability of infection of an individual calf and a 52 or 99.99% probability of infection of the group. Anti-Chlamydophila immunoglobulin M antibodies in Chlamydophila PCR-positive calves and dams and in dams that gave birth to calves that later became positive were significantly higher than in PCR-negative animals (P </= 0.02). Collectively, crowding strongly enhances the frequency and intensity of highly prevalent Chlamydophila infections in cattle.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.