Evidence map›Paper›PMID 15583292›Full record

ArticleJournal of clinical microbiology2004

Phylogeny and evolution of medical species of Candida and related taxa: a multigenic analysis.

Stephanie Diezmann, Cymon J Cox, Gabriele Schönian, Rytas J Vilgalys, Thomas G Mitchell

Open access · greenAbstract read
In one paragraph

Article in Journal of clinical microbiology, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 58 papers.

0numbers the graph read from it
0cells of the map it votes in
58citing papers in PubMed
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

58 citing papers in PubMed, 131 citations in OpenAlex.

  1. UnmaskingPathogens (Basel, Switzerland) · 2026
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  2. CRISPR-based synthetic biology toolkit development inSynthetic and systems biotechnology · 2026
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  8. Central Carbon Metabolism inJournal of fungi (Basel, Switzerland) · 2024
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  9. Molecular Detection ofJournal of fungi (Basel, Switzerland) · 2023
    Article
  10. Medical mycology case reports · 2023
    Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. Article
  17. Article
  18. Candida auris: an Emerging Fungal Pathogen.Journal of clinical microbiology · 2018
    Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Stephanie DiezmannDepartment of Biology, Duke University Medical Center, Durham, NC 27710, USA. sd21@duke.edu
Cymon J Cox
Gabriele Schönian
Rytas J Vilgalys
Thomas G Mitchell
Duke University · USCharité - Universitätsmedizin Berlin · DEDuke University Hospital · US

Funding

MOLECULAR IDENTIFICATION OF PATHOGENIC FUNGIR01AI028836 · NIAID · DUKE UNIVERSITY · PI MITCHELL, THOMAS G. · 1991 to 2000
$304k
NIAID NIH HHS AI 28836
6 · The paper itself

Abstract

Hemiascomycetes are species of yeasts within the order Saccharomycetales. The order encompasses disparate genera with a variety of life styles, including opportunistic human pathogens (e.g., Candida albicans), plant pathogens (e.g., Eremothecium gossypii), and cosmopolitan yeasts associated with water and decaying vegetation. To analyze the phylogeny of medically important species of yeasts, we selected 38 human pathogenic and related strains in the order Saccharomycetales. The DNA sequences of six nuclear genes were analyzed by maximum likelihood and Bayesian phylogenetic methods. The maximum likelihood analysis of the combined data for all six genes resolved three major lineages with significant support according to Bayesian posterior probability. One clade was mostly comprised of pathogenic species of Candida. Another major group contained members of the family Metschnikowiaceae as a monophyletic group, three species of Debaryomyces, and strains of Candida guilliermondii. The third clade consisted exclusively of species of the family Saccharomycetaceae. Analysis of the evolution of key characters indicated that both codon reassignment and coenzyme Q(9) likely had single origins with multiple losses. Tests of correlated character evolution revealed that these two traits evolved independently.

Indexed as

Evolution, MolecularPhylogenyBayes TheoremCandidaCandidiasisDNA, RibosomalFungal ProteinsHumansMonte Carlo MethodRNA, Ribosomal, 16SRNA, Ribosomal, 18SSaccharomycetalesDNA, RibosomalFungal ProteinsRNA, Ribosomal, 16SRNA, Ribosomal, 18S

Identifiers

PMID15583292
PMCPMC535224
OpenAlexW2102148372

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.