ArticleBioorganic & medicinal chemistry2005
Boronic acid fluorescent sensors for monosaccharide signaling based on the 6-methoxyquinolinium heterocyclic nucleus: progress toward noninvasive and continuous glucose monitoring.
Article in Bioorganic & medicinal chemistry, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
20 citing papers in PubMed, 80 citations in OpenAlex.
- Subdermal Insertable Sensors for Health Monitoring: Applications, Challenges, and Emerging Technologies.Annals of biomedical engineering · 2026Review
- Water-soluble fluorescent chemosensor for sorbitol based on a dicationic diboronic receptor. Crystal structure and spectroscopic studies.RSC advances · 2023Article
- An alkaline phosphatase-induced immunosensor for SARS-CoV-2 N protein and cardiac troponin I based on the in situ fluorogenic self-assembly between N-heterocyclic boronic acids and alizarin red S.Sensors and actuators. B, Chemical · 2023Article
- Ophthalmic Sensors and Drug Delivery.ACS sensors · 2021Review
- Sodium-Sensitive Contact Lens for Diagnostics of Ocular Pathologies.Sensors and actuators. B, Chemical · 2021Article
- Fluorescent contact lens for continuous non-invasive measurements of sodium and chloride ion concentrations in tears.Analytical biochemistry · 2020Article
- Boronic Acid Appended Naphthyl-Pyridinium Receptors as Chemosensors for Sugars.Scientific reports · 2019Article
- Recent development of boronic acid-based fluorescent sensors.RSC advances · 2018Review
- Contact lens to measure individual ion concentrations in tears and applications to dry eye disease.Analytical biochemistry · 2018Article
- Glucose Sensing for Diabetes Monitoring: Recent Developments.Sensors (Basel, Switzerland) · 2017Review
- Crystal structure of 3-benzamido-1-(4-nitro-benz-yl)quinolinium tri-fluoro-methane-sulfonate.Acta crystallographica. Section E, Crystallographic communications · 2016Article
- Estimation of Dipole Moments and Quantum Yield of 5-chloro-2-methoxyphenyl Boronic Acid in Different Solvents Environment.Journal of fluorescence · 2015Article
- Method for analysis of different oligosacchiride structures.Journal of fluorescence · 2012Article
- Carbohydrate recognition by boronolectins, small molecules, and lectins.Medicinal research reviews · 2010Review
- Effect of extended conjugation with a phenylethynyl group on the fluorescent properties of water-soluble arylboronic acids.Tetrahedron · 2007Article
- Wavelength-ratiometric near-physiological pH sensors based on 6-aminoquinolinium boronic acid probes.Talanta · 2005Article
- A glucose-sensing contact lens: from bench top to patient.Current opinion in biotechnology · 2005Review
- OPHTHALMIC GLUCOSE MONITORING USING DISPOSABLE CONTACT LENSES.Reviews in fluorescence · 2005Article
- Fluorescence intensity and lifetime-based cyanide sensitive probes for physiological safeguard.Analytica chimica acta · 2004Article
- Ophthalmic glucose monitoring using disposable contact lenses--a review.Journal of fluorescence · 2004Review
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
Abstract
The synthesis, characterization, and spectral properties of strategically designed boronic acid containing fluorescent sensors, o-, m-, p-BMOQBA, for the potential detection of tear glucose concentrations when immobilized in plastic disposable contact lenses is described. The new probes, BMOQBAs, consist of the 6-methoxyquinolinium nucleus as a fluorescent indicator, and the boronic acid moiety as a glucose chelating group. A control compound BMOQ, which has no boronic acid group and therefore does not bind monosaccharides has also been prepared. In this paper, we show that structural design considerations of the new probes have afforded for their compatibility within the lenses, with reduced probe sugar-bound pK(a) favorable with the mildly acidic lens environment. In addition, the new probes are readily water soluble, have high quantum yields, and can be prepared by a simple one-step synthetic procedure.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.