Evidence map›Paper›PMID 15580329›Full record

ArticleDer Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen2004

[Anastomotic leakage in the gastrointestinal tract-repair and prognosis].

M Stumpf, U Klinge, P R Mertens

Abstract readEnglish Abstract
PubMed Publisher
In one paragraph

Article in Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.2field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 14 citations in OpenAlex.

  1. Surgical sutures: coincidence or experience?Hernia : the journal of hernias and abdominal wall surgery · 2017
    Article
  2. Article
  3. Article
  4. [Anastomotic techniques for the gastrointestinal tract].Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen · 2013
    Review
  5. Article
  6. [Intestinal anastomoses and techniques in the lower gastrointestinal tract].Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen · 2011
    Review
  7. [Surgery for rectal cancer].Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen · 2009
    Review
  8. Collagen in colon disease.Hernia : the journal of hernias and abdominal wall surgery · 2006
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

M StumpfChirurgische Klinik, Universitätsklinikum der RWTH Aachen. m.stumpf@chir.rwth-aachen.de
U Klinge
P R Mertens
Universitätsklinikum Aachen · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Anastomotic leakage is still a serious complication in surgery, resulting in increased morbidity and mortality. The reasons for its onset are various and due to two main reasons: general risk factors of the individual patient and technical surgical factors influencing the outcome after gastrointestinal anastomoses. Changes in the extracellular matrices, particularly due to collagen metabolism, and related disturbances are assumed to be important factors influencing wound healing processes. The technique chosen and the surgical skill are important with regard to inflammation and tissue necroses at the anastomotic line. Analysis of data obtained by clinical studies that concern clinical risk factors for anastomotic leakage reveal an inhomogeneous picture. Attempts to develop risk profiles or scores based on these results have failed until now. Problems encompass the complexity of wound healing processes, and it is questionable whether our current knowledge about them is complete. Therefore, profound understanding of anastomotic leakage requires in-depth analysis of the interaction of extracellular matrix components. Preliminary results indicate the presence of a risk population with collagen metabolism disturbances that have a major effect on wound healing after gastrointestinal anastomosis.

Indexed as

Wound HealingAlcohol DrinkingAnastomosis, SurgicalClinical Trials as TopicCollagenExtracellular MatrixFemaleGastrointestinal TractHumansMaleMatrix MetalloproteinasesNutritional Physiological PhenomenaPeritonitisPrognosisRandomized Controlled Trials as TopicRetrospective StudiesCollagenMatrix Metalloproteinases

Identifiers

PMID15580329
OpenAlexW139525804

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.