Evidence map›Paper›PMID 15578213›Full record

ArticlePflugers Archiv : European journal of physiology2005

An air-molding technique for fabricating PDMS planar patch-clamp electrodes.

Kathryn G Klemic, James F Klemic, Fred J Sigworth

Abstract read
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In one paragraph

Article in Pflugers Archiv : European journal of physiology, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Article
  3. Cardiac optogenetics.American journal of physiology. Heart and circulatory physiology · 2013
    Review
  4. Article
  5. Article
  6. Article
  7. Mammalian electrophysiology on a microfluidic platform.Proceedings of the National Academy of Sciences of the United States of America · 2005
    Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Kathryn G KlemicDepartment of Cellular and Molecular Physiology, Yale University, New Haven, CT, 06520, USA.
James F Klemic
Fred J Sigworth

Funding

New Technologies for Patch-Clamp RecordingR01EB002020 · NIBIB · YALE UNIVERSITY · PI SIGWORTH, FREDERICK J · 2003 to 2005
$833k
NIBIB NIH HHS EB-002020
6 · The paper itself

Abstract

We present a new technique for fabricating planar patch electrodes in the laboratory. Planar electrodes are micromolded using a micron-sized stream of air to define an aperture in the silicone elastomer, polydimethylsiloxane (PDMS). We have previously demonstrated that planar PDMS electrodes make excellent patch electrodes after surface modification. We demonstrate single-channel measurements of the rSlo channel in Xenopus oocytes and whole-cell measurements in CHO and RBL mammalian cell lines, using planar PDMS electrodes.

Indexed as

MicroelectrodesAirAnimalsCHO CellsCricetinaeEquipment DesignFemaleMembrane PotentialsOocytesPatch-Clamp TechniquesXenopus laevis

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.