ArticleGenome research2004
Contribution of Asian mouse subspecies Mus musculus molossinus to genomic constitution of strain C57BL/6J, as defined by BAC-end sequence-SNP analysis.
Article in Genome research, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers.
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Who cites it
45 citing papers in PubMed.
- Comparative sequence analysis of the mouse pseudoautosomal region from three inbred strains reveals it to be the most rapidly evolving 'chromosome'.Proceedings of the Japan Academy. Series B, Physical and biological sciences · 2026Article
- Genic and chromosomal components of Prdm9-driven hybrid male sterility in mice (Mus musculus).Genetics · 2022Article
- A wild-derived inbred mouse strain, MSM/Ms, provides insights into novel skin tumor susceptibility genes.Experimental animals · 2021Article
- Review
- Prdm9 Intersubspecific Interactions in Hybrid Male Sterility of House Mouse.Molecular biology and evolution · 2020Article
- Large X-Linked Palindromes Undergo Arm-to-Arm Gene Conversion across Mus Lineages.Molecular biology and evolution · 2020Article
- Hepatic Sdf2l1 controls feeding-induced ER stress and regulates metabolism.Nature communications · 2019Article
- Genetic and morphometric characteristics of Korean wild mice (KWM/Hym) captured at Chuncheon, South Korea.Laboratory animal research · 2018Article
- A tissue-specific self-interacting chromatin domain forms independently of enhancer-promoter interactions.Nature communications · 2018Article
- Tmc2 expression partially restores auditory function in a mouse model of DFNB7/B11 deafness caused by loss of Tmc1 function.Scientific reports · 2018Article
- NIG_MoG: a mouse genome navigator for exploring intersubspecific genetic polymorphisms.Mammalian genome : official journal of the International Mammalian Genome Society · 2015Article
- Tracing the eastward dispersal of the house mouse, Mus musculus.Genes and environment : the official journal of the Japanese Environmental Mutagen Society · 2015Review
- In quest of genomic treasure.The Journal of reproduction and development · 2015Article
- Genetic dissection of the ity3 locus identifies a role for ncf2 co-expression modules and suggests selp as a candidate gene underlying the ity3.2 locus.Frontiers in immunology · 2014Article
- Article
- Article
- The ancestor of extant Japanese fancy mice contributed to the mosaic genomes of classical inbred strains.Genome research · 2013Article
- Genetic and phenotypic characterization of a Japanese wild-derived DOB/Oda rat strain.Mammalian genome : official journal of the International Mammalian Genome Society · 2013Article
- Gene-trap mutagenesis using Mol/MSM-1 embryonic stem cells from MSM/Ms mice.Mammalian genome : official journal of the International Mammalian Genome Society · 2013Article
- Chromosome substitution strains: gene discovery, functional analysis, and systems studies.Mammalian genome : official journal of the International Mammalian Genome Society · 2012Review
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Authors and funding
12 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
MSM/Ms is an inbred strain derived from the Japanese wild mouse, Mus musculus molossinus. It is believed that subspecies molossinus has contributed substantially to the genome constitution of common laboratory strains of mice, although the majority of their genome is derived from the west European M. m. domesticus. Information on the molossinus genome is thus essential not only for genetic studies involving molossinus but also for characterization of common laboratory strains. Here, we report the construction of an arrayed bacterial artificial chromosome (BAC) library from male MSM/Ms genomic DNA, covering approximately 1x genome equivalent. Both ends of 176,256 BAC clone inserts were sequenced, and 62,988 BAC-end sequence (BES) pairs were mapped onto the C57BL/6J genome (NCBI mouse Build 30), covering 2,228,164 kbp or 89% of the total genome. Taking advantage of the BES map data, we established a computer-based clone screening system. Comparison of the MSM/Ms and C57BL/6J sequences revealed 489,200 candidate single nucleotide polymorphisms (SNPs) in 51,137,941 bp sequenced. The overall nucleotide substitution rate was as high as 0.0096. The distribution of SNPs along the C57BL/6J genome was not uniform: The majority of the genome showed a high SNP rate, and only 5.2% of the genome showed an extremely low SNP rate (percentage identity = 0.9997); these sequences are likely derived from the molossinus genome.
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