Evidence map›Paper›PMID 15569242›Full record

ReviewTraffic (Copenhagen, Denmark)2005

Covert operations of uropathogenic Escherichia coli within the urinary tract.

Jean M Bower, Danelle S Eto, Matthew A Mulvey

Open access · bronzeAbstract readReview
In one paragraph

Review in Traffic (Copenhagen, Denmark), 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 62 papers.

0numbers the graph read from it
0cells of the map it votes in
62citing papers in PubMed
2.9field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

62 citing papers in PubMed, 150 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Review
  6. Review
  7. Article
  8. Article
  9. Article
  10. Peptidoglycan Endopeptidase Spr of UropathogenicFrontiers in microbiology · 2020
    Article
  11. Review
  12. Article
  13. Article
  14. A Porcine Model for Urinary Tract Infection.Frontiers in microbiology · 2019
    Article
  15. Review
  16. Article
  17. The Prevalence of Virulence Genes and Virulotypes ofIranian journal of public health · 2018
    Article
  18. Review
  19. Activation of the NLRP3 Inflammasome Pathway by UropathogenicFrontiers in cellular and infection microbiology · 2018
    Article
  20. Article

2 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Jean M BowerPathology Department, Division of Cell Biology and Immunology, University of Utah School of Medicine, 30 North 1900 East, Salt Lake City, Utah 84132-2501, USA.
Danelle S Eto
Matthew A Mulvey
University of Utah · US

Funding

Training Program in Microbial PathogenesisT32AI055434 · NIAID · UTAH STATE HIGHER EDUCATION SYSTEM--UNIVERSITY OF UTAH · PI MULVEY, MATTHEW A, PLANELLES, VICENTE · 2004 to 2025
$6.0M
Bacterial Invasion and Trafficking within the BladderR01DK068585 · NIDDK · UNIVERSITY OF UTAH · PI MULVEY, MATTHEW A · 2004 to 2010
$2.4M
Control of bladder infections by NF-kappaBR21DK069526 · NIDDK · UNIVERSITY OF UTAH · PI MULVEY, MATTHEW A · 2004 to 2005
$336k
NIAID NIH HHS T32 AI055434NIDDK NIH HHS DK068585-01NIDDK NIH HHS R01 DK068585NIDDK NIH HHS R21 DK069526
6 · The paper itself

Abstract

Entry into host cells is required for many bacterial pathogens to effectively disseminate within a host, avoid immune detection and cause disease. In recent years, many ostensibly extracellular bacteria have been shown to act as opportunistic intracellular pathogens. Among these are strains of uropathogenic Escherichia coli (UPEC), the primary causative agents of urinary tract infections (UTIs). UPEC are able to transiently invade, survive and multiply within the host cells and tissues constituting the urinary tract. Invasion of host cells by UPEC is promoted independently by distinct virulence factors, including cytotoxic necrotizing factor, Afa/Dr adhesins, and type 1 pili. Here we review the diverse mechanisms and consequences of host cell invasion by UPEC, focusing also on the impact of these processes on the persistence and recurrence of UTIs.

Indexed as

Adhesins, Escherichia coliAnimalsBacterial AdhesionBacterial ToxinsEscherichia coliEscherichia coli InfectionsEscherichia coli ProteinsFimbriae, BacterialHumansKidneyModels, BiologicalUrinary BladderUrinary TractUrinary Tract InfectionsVirulenceAdhesins, Escherichia coliBacterial Toxinscytotoxic necrotizing factor type 1Escherichia coli Proteins

Identifiers

PMID15569242
PMCPMC2523259
OpenAlexW2068760392

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.