Evidence map›Paper›PMID 15566589›Full record

ArticleCritical care (London, England)2004

Early postoperative hyperglycaemia is not a risk factor for infectious complications and prolonged in-hospital stay in patients undergoing oesophagectomy: a retrospective analysis of a prospective trial.

Titia M Vriesendorp, J Hans DeVries, Jan B F Hulscher, Frits Holleman, Jan J van Lanschot, Joost B L Hoekstra

Open access · goldAbstract read
In one paragraph

Article in Critical care (London, England), 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it, 37 citations in OpenAlex.

  1. Insulin for glycaemic control in acute ischaemic stroke.The Cochrane database of systematic reviews · 2014
    Pooled it
  2. Article
  3. Article
  4. Early postoperative hyperglycemia as a predictor of postoperative infectious complications and overall survival in non-diabetic patients with esophageal cancer.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2023
    Article
  5. Article
  6. Article
  7. Review
  8. Observational
  9. Hyperglycemia 3 days after esophageal cancer surgery is associated with an increased risk of postoperative infection.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2014
    Article
  10. Article
  11. Article
  12. Glucose metabolism in cardiovascular surgery.HSR proceedings in intensive care & cardiovascular anesthesia · 2010
    Article
  13. Surgical site infections following colorectal surgery in patients with diabetes: association with postoperative hyperglycemia.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2009
    Article
  14. Article
  15. Review
  16. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Titia M VriesendorpDepartment of Internal Medicine, Academic Medical Centre, Amsterdam, The Netherlands. T.M.Vriesendorp@amc.uva.nl
J Hans DeVries
Jan B F Hulscher
Frits Holleman
Jan J van Lanschot
Joost B L Hoekstra
Academic Medical Center · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionTreating hyperglycaemia in hospitalized patients has proven to be beneficial, particularly in those with obstructive vascular disease. In a cohort of patients undergoing resection for oesophageal carcinoma (a group of patients with severe surgical stress but a low prevalence of vascular disease), we investigated whether early postoperative hyperglycaemia is associated with increased incidence of infectious complications and prolonged in-hospital stay.

methodsPostoperative glucose values up to 48 hours after surgery were retrieved for 151 patients with American Society of Anesthesiologists class I or II who had been previously included in a randomized trial conducted in a tertiary referral hospital. Multivariate regression analysis was used to define the independent contribution of possible risk factors selected by univariate analysis.

resultsIn univariate regression analysis, postoperative glucose levels were associated with increased length of in-hospital stay (P < 0.001) but not with infectious complications (P = 0.21). However, postoperative glucose concentration was not found to be an independent risk factor for prolonged in-hospital stay in multivariate analysis (P = 0.20).

conclusionOur data indicate that postoperative hyperglycaemia is more likely to be a risk marker than a risk factor in patients undergoing highly invasive surgery for oesophageal cancer. We hypothesize that patients with a low prevalence of vascular disease may benefit less from intensive insulin therapy.

Indexed as

AdenocarcinomaAgedBlood GlucoseComorbidityEsophageal NeoplasmsEsophagectomyFemaleHumansHyperglycemiaIntensive Care UnitsLength of StayMaleMiddle AgedMultivariate AnalysisNetherlandsRandomized Controlled Trials as TopicBlood Glucose

Identifiers

PMID15566589
PMCPMC1065066
OpenAlexW2097923332

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.