Evidence map›Paper›PMID 15565387›Full record

Trial reportDer Anaesthesist2005

[Total intravenous anesthesia with propofol and remifentanil. Results of a multicenter study of 6,161 patients].

J Schmidt, W Hering, S Albrecht

Abstract readClinical TrialClinical Trial, Phase IVMulticenter Study
PubMed Publisher
In one paragraph

Trial report in Der Anaesthesist, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
2.2field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 16 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. Intraoperative motor evoked potential monitoring: overview and update.Journal of clinical monitoring and computing · 2006
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

J SchmidtKlinik für Anästhesiologie, Friedrich-Alexander-Universität, Erlangen-Nürnberg. joachim.schmidt@kfa.imed.uni-erlangen.de
W Hering
S Albrecht
Friedrich-Alexander-Universität Erlangen-Nürnberg · DEMarienkrankenhaus Hamburg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThe aim of this study was to investigate efficacy and tolerability of propofol, remifentanil and cisatracurium or mivacurium in routine anesthetic practice. PATIENTS AND

methodsA total of 6,161 patients scheduled for abdominal or orthopedic surgery were included in this open multicenter phase IV study. Perioperative hemodynamics as well as induction, recovery and discharge times, anesthetics, frequency of PONV and side-effects were studied.

resultsQuality of induction and maintenance of anesthesia were evaluated by anesthesiologists to be good or very good in 88%. 86% of the patients assessed anesthesia as good or very good. Adverse events were reported for 28 patients (0.45%), with hypotension and bradycardia being most frequent. Recovery was evaluated by anesthesiologists to be good or very good in 88%, surgeons and nursing staff assessed the TIVA as good or very good in 90%. Most frequent postoperative complaints were pain (16.7%), nausea (6.1%), shivering (3.1%) and vomiting (0.7%).

conclusionsThe study showed that total intravenous anesthesia using propofol, remifentanil and cisatracurium or mivacurium is safe, tolerable and effective and has a high degree of acceptance.

Indexed as

Anesthesia, IntravenousAnesthetics, IntravenousPiperidinesPropofolAbdomenAdultAgedAtracuriumFemaleHemodynamicsHumansIsoquinolinesMaleMiddle AgedMivacuriumMonitoring, IntraoperativeAnesthetics, IntravenousAtracuriumIsoquinolinesMivacuriumNeuromuscular Nondepolarizing AgentsPiperidinesPropofolRemifentanil

Identifiers

PMID15565387
OpenAlexW131225391

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.