Evidence map›Paper›PMID 15565362›Full record

Trial reportIntensive care medicine2005

Analysis of blood glucose measurements using capillary and arterial blood samples in intensive care patients.

Atul Kulkarni, Manoj Saxena, Grant Price, Michael J O'Leary, Theresa Jacques, John A Myburgh

Registry-linked trialAbstract readClinical Trial
PubMed Publisher
In one paragraph

Trial report in Intensive care medicine, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01176279 (Randomised Clinical Trial to Evaluate the Obtention of Blood Samples Through an Arterial Catheter to Monitor Glycose Levels), which is not on this map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01176279 phase4unknown statusnot on this mapstarted 2008, after this paper: background citation

Randomised Clinical Trial to Evaluate the Obtention of Blood Samples Through an Arterial Catheter to Monitor Glycose Levels

TypeinterventionalSponsorConsorci Hospitalari de VicRan2008 to 2011Enrolled100ConditionsCritical Illness, HyperglycemiaArmsManual and automated washing of the peripherical lines, Automated washing of the peripherical lines
3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 88 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Validity of bedside blood glucose measurement in critically ill patients with intensive insulin therapy.Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2016
    Article
  5. Review
  6. Observational
  7. Review
  8. Article
  9. Article
  10. Article
  11. An overview of hypoglycemia in the critically ill.Journal of diabetes science and technology · 2009
    Review
  12. Accuracy of different methods for blood glucose measurement in critically ill patients.Sao Paulo medical journal = Revista paulista de medicina · 2009
    Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Atul KulkarniDepartment of Intensive Care Medicine, St. George Hospital, Gray Street, Kogarah, 2217 Sydney, Australia.
Manoj Saxena
Grant Price
Michael J O'Leary
Theresa Jacques
John A Myburgh
St George Hospital · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo analyse agreement between two methods for blood glucose measurement in intensive care patients: capillary blood using a reagent strip and glucometer with arterial blood using a blood gas analyser. DESIGN AND

settingProspective, single-centre, observational study in a 12-bed tertiary referral intensive care unit. MEASUREMENTS: Blood glucose levels were measured in consecutive patients using simultaneous measurements of capillary blood samples using glucometry and from a multi-electrode arterial blood gas analyser. An a priori subgroup of patients with tissue hypoperfusion was identified (defined as systolic blood pressure <90 mmHg or vasopressor dependency). A total of 493 paired measurements were obtained; 75 of these were from patients with systemic hypoperfusion.

resultsOverall, the mean difference (bias) was 0.12 mmol/l (2.15 mg/dl) and precision 0.77 mmol/l (13.8 mg/dl); 95% limits of agreement were -0.14 and 1.66 mmol/l (-2.5 and 29.8 mg/dl). In patients with systemic hypoperfusion the bias was 0.24 mmol/l (4.0 mg/dl) and precision 0.9 mmol/l (16.2 mg/dl); 95% limits of agreement -2.05 and 1.58 mmol/l (36.8 and 28.4 mg/dl).

conclusionsIn a general population of intensive care patients, there is statistical agreement between blood glucose measured from capillary blood glucometry and arterial blood gas analysis. However, in patients with systemic hypoperfusion, the accuracy of agreement between these two measurement techniques may be such that that biochemical hypoglycaemia (<2.5 mmol/l, 44.9 mg/dl) may go undetected if used interchangeably.

Indexed as

Blood GlucosePoint-of-Care SystemsAdultAgedAged, 80 and overBlood Gas AnalysisCritical CareFemaleHumansMaleMiddle AgedProspective StudiesBlood Glucose

Identifiers

PMID15565362
OpenAlexW2085190680

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.