ArticleThorax2004
Continuous and intermittent exercise responses in individuals with chronic obstructive pulmonary disease.
Article in Thorax, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 20 papers, 5 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Effect of the VitaBreath Device on Chest Wall Dynamic Hyperinflation and Respiratory Muscle Activation During Recovery From Exercise in Patients With Chronic Obstructive Pulmonary Disease
Comparison of Clinical and Physiological Response Among Three Modalities of Exercise Training in COPD With Chronic Respiratory Failure (CRF)
Who cites it
20 citing papers in PubMed, 5 syntheses or guidelines pooled it.
- Fixed-intensity exercise tests to measure exertional dyspnoea in chronic heart and lung populations: a systematic review.European respiratory review : an official journal of the European Respiratory Society · 2023Pooled it
- Effects of High-Intensity Interval Training on Pulmonary Function and Exercise Capacity in Individuals with Chronic Obstructive Pulmonary Disease: A Meta-Analysis and Systematic Review.Advances in therapy · 2022Pooled it
- Optimal intensity and type of leg exercise training for people with chronic obstructive pulmonary disease.The Cochrane database of systematic reviews · 2011Pooled it
- Effect of interval compared to continuous exercise training on physiological responses in patients with chronic respiratory diseases: A systematic review and meta-analysis.Chronic respiratory diseasePooled it
- Optimal intensity and type of lower limb aerobic training for patients with chronic obstructive pulmonary disease: a systematic review and network meta-analysis of RCTs.Therapeutic advances in respiratory diseasePooled it
- Effects of Long-Term Regular Continuous and Intermittent Walking on Oxidative Stress, Metabolic Profile, Heart Rate Variability, and Blood Pressure in Older Adults with Hypertension.Journal of environmental and public health · 2022Trial
- Continuous exercise induces airway epithelium damage while a matched-intensity and volume intermittent exercise does not.Respiratory research · 2019Trial
- Pulmonary Rehabilitation in Patients with Operable Non-Small Cell Lung Cancer.Journal of clinical medicine · 2025Review
- Upper-limb intervalERJ open research · 2024Article
- Participants' experiences of the benefits, barriers and facilitators of attending a community-based exercise programme for people with chronic obstructive pulmonary disease.Health & social care in the community · 2020Article
- Exponential model for analysis of heart rate responses and autonomic cardiac modulation during different intensities of physical exercise.Royal Society open science · 2019Article
- Intermittent Use of Portable NIV Increases Exercise Tolerance in COPD: A Randomised, Cross-Over Trial.Journal of clinical medicine · 2019Article
- Secondary elements of blood pH variation can influence the effort effectiveness based on adaptive changes within a group of elite athletes.Clujul medical (1957) · 2016Article
- Time to adapt exercise training regimens in pulmonary rehabilitation--a review of the literature.International journal of chronic obstructive pulmonary disease · 2014Review
- Comparison of physiological and perceptual responses between continuous and intermittent cycling.Journal of human kinetics · 2011Article
- Effectiveness of Interval Exercise Training in Patients with COPD.Cardiopulmonary physical therapy journal · 2010Article
- Exercise: the brittle cornerstone of type 2 diabetes treatment.Diabetologia · 2008Article
- New modalities of pulmonary rehabilitation in patients with chronic obstructive pulmonary disease.Sports medicine (Auckland, N.Z.) · 2007Review
- Is there any treatment other than drugs to alleviate dyspnea in COPD patients?International journal of chronic obstructive pulmonary disease · 2006Review
- Greater exercise tolerance in COPD during acute intermittent compared to continuous shuttle walking protocols: A proof-of-concept study.Chronic respiratory diseaseArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundWhile the acute physiological responses to continuous exercise have been well documented in individuals with chronic obstructive pulmonary disease (COPD), no previous study has examined the response to intermittent exercise in these patients.
methodsWe examined the physiological responses of 10 individuals with moderate COPD (forced expiratory volume in 1 second 52 (15)% predicted) who performed both an intermittent (1 min exercise and rest intervals) and a continuous cycle ergometer test on separate days. Both intermittent and continuous exercise tests were performed at the same power output, calculated as 70% of the peak power attained during an incremental exercise test.
resultsIntermittent exercise was associated with significantly lower values for oxygen uptake, carbon dioxide output, expired ventilation, heart rate, plasma lactate concentration, and ratings of breathlessness than continuous exercise. Subjects were able to complete a significantly greater total amount of work during intermittent exercise (71 (32) kJ) than during continuous exercise (31 (24) kJ). The degree of dynamic lung hyperinflation (change in end expiratory lung volume) was significantly lower during intermittent exercise (0.23 (0.07) l) than in continuous exercise (0.52 (0.13) l).
conclusionsThe greater amount of work performed and lower measured physiological responses achieved with intermittent exercise may allow for greater peripheral training adaptations in individuals with more limited lung function. The results suggest that intermittent exercise may be superior to continuous exercise as a mode of training for patients with COPD.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.