ArticlePlant physiology2004
Effect of the Colorless non-ripening mutation on cell wall biochemistry and gene expression during tomato fruit development and ripening.
Article in Plant physiology, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 75 papers.
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Who cites it
75 citing papers in PubMed, 175 citations in OpenAlex.
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- Cytokinin negatively regulates tomato fruit ripening by influencing the ethylene pathway.Plant cell reports · 2025Article
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- Genetic tapestry of Capsicum fruit colors: a comparative analysis of four cultivated species.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2024Article
- Epigenetic insights into an epimutantFrontiers in plant science · 2024Review
- An Integrative Transcriptomics and Proteomics Approach to Identify Putative Genes Underlying Fruit Ripening in Tomato near Isogenic Lines with Long Shelf Life.Plants (Basel, Switzerland) · 2023Article
- Cell Wall Integrity Signaling in Fruit Ripening.International journal of molecular sciences · 2023Review
- Genome-Wide Identification of the SQUAMOSA Promoter-Binding Protein-like (SPL) Transcription Factor Family in Sweet Cherry Fruit.International journal of molecular sciences · 2023Article
- Epigenetic regulation in tomato fruit ripening.Frontiers in plant science · 2023Review
- Identification of a novel locusFrontiers in genetics · 2023Article
- An overview of ethylene insensitive tomato mutants: Advantages and disadvantages for postharvest fruit shelf-life and future perspective.Frontiers in plant science · 2023Review
- Proteomic Changes in Response toPlants (Basel, Switzerland) · 2022Article
- Silencing of the Target of Rapamycin Complex Genes Stimulates Tomato Fruit Ripening.Molecules and cells · 2022Article
- Comparative metabolomic and transcriptomic analysis reveals a coexpression network of the carotenoid metabolism pathway in the panicle of Setaria italica.BMC plant biology · 2022Article
- Multispecies transcriptomes reveal core fruit development genes.Frontiers in plant science · 2022Article
- A tomato LATERAL ORGAN BOUNDARIES transcription factor,Proceedings of the National Academy of Sciences of the United States of America · 2021Article
- Role of MdERF3 and MdERF118 natural variations in apple flesh firmness/crispness retainability and development of QTL-based genomics-assisted prediction.Plant biotechnology journal · 2021Article
- Host susceptibility factors render ripe tomato fruit vulnerable to fungal disease despite active immune responses.Journal of experimental botany · 2021Article
15 more citing papers are in PubMed but not listed here.
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Authors and funding
8 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The Colorless non-ripening (Cnr) mutation in tomato (Solanum lycopersicum) results in mature fruits with colorless pericarp tissue showing an excessive loss of cell adhesion (A.J. Thompson, M. Tor, C.S. Barry, J. Vrebalov, C. Orfila, M.C. Jarvis, J.J. Giovannoni, D. Grierson, G.B. Seymour [1999] Plant Physiol 120: 383-390). This pleiotropic mutation is an important tool for investigating the biochemical and molecular basis of cell separation during ripening. This study reports on the changes in enzyme activity associated with cell wall disassembly in Cnr and the effect of the mutation on the program of ripening-related gene expression. Real-time PCR and biochemical analysis demonstrated that the expression and activity of a range of cell wall-degrading enzymes was altered in Cnr during both development and ripening. These enzymes included polygalacturonase, pectinesterase (PE), galactanase, and xyloglucan endotransglycosylase. In the case of PE, the protein product of the ripening-related isoform PE2 was not detected in the mutant. In contrast with wild type, Cnr fruits were rich in basic chitinase and peroxidase activity. A microarray and differential screen were used to profile the pattern of gene expression in wild-type and Cnr fruits. They revealed a picture of the gene expression in the mutant that was largely consistent with the real-time PCR and biochemical experiments. Additionally, these experiments demonstrated that the Cnr mutation had a profound effect on many aspects of ripening-related gene expression. This included a severe reduction in the expression of ripening-related genes in mature fruits and indications of premature expression of some of these genes in immature fruits. The program of gene expression in Cnr resembles to some degree that found in dehiscence or abscission zones. We speculate that there is a link between events controlling cell separation in tomato, a fleshy fruit, and those involved in the formation of dehiscence zones in dry fruits.
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