Evidence map›Paper›PMID 1556233›Full record

ArticleJournal of clinical pathology1992

Fibroepithelial polyps of the vagina: are they old granulation tissue polyps?

T B Halvorsen, E Johannesen

Open access · greenAbstract read
In one paragraph

Article in Journal of clinical pathology, 1992. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact, top 86% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 59 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Fibroepithelial Polyps of the Vagina in Pregnancy.Journal of clinical and diagnostic research : JCDR · 2015
    Article
  9. Vaginal polyp in a newborn.European journal of pediatrics · 2008
    Article
  10. Fibroepithelial polyp of the prepuce: A rare complication of long-term condom catheter usage.Indian journal of urology : IJU : journal of the Urological Society of India · 2008
    Article
  11. Fibroepithelial Polyp of the Vagina in Pregnancy: A Case Report.Journal of the West African College of Surgeons
    Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

T B HalvorsenDepartment of Pathology, Trondheim University Hospital, Norway.
E Johannesen
St Olav's University Hospital · NO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimsTo study the nature of fibroepithelial polyps of the vagina.

methodsSixty five fibroepithelial polyps of the vagina and 64 granulation tissue polyps diagnosed over 15 years were reviewed histologically.

resultsCytologically benign multinucleated stromal cells were present in large numbers in 19 of the fibroepithelial polyps of the vagina (FEPV). Only one polyp contained atypical stromal cells, a high mitotic count, and abnormal mitoses and was indistinguishable from a malignant tumour. Immunostaining showed the presence of vimentin and desmin positive mono- and multinucleated stromal cells in FEPV and occasional oestrogen receptor positive nuclei. Desmin positive cells could not be shown in granulation tissue polyps.

conclusionsFEPV are common lesions with benign mono- and multinucleated fibroblastic stromal cells in which myoid differentiation is often present. FEPV may develop as a result of a granulation tissue reaction after some local injury of the vaginal mucosa. Hormonal factors may modulate the growth of FEPVs. Delayed differentiation of myofibroblastic cells may explain why granulation tissue sometimes does not contract properly but turns into polyps.

Indexed as

AdolescentAdultAgedAged, 80 and overCell NucleusChildChild, PreschoolFemaleGranulation TissueHumansImmunoenzyme TechniquesMast CellsMiddle AgedMitosisPolypsVaginal Neoplasms

Identifiers

PMID1556233
PMCPMC495483
OpenAlexW2065587520

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.