Evidence map›Paper›PMID 15561873›Full record

ArticleAntimicrobial agents and chemotherapy2004

PCR-restriction fragment length polymorphism assay for detection of gyrA mutations associated with fluoroquinolone resistance in Campylobacter coli.

Rodrigo Alonso, Estibaliz Mateo, Cecilia Girbau, Estibaliz Churruca, Irati Martinez, Aurora Fernández-Astorga

Open access · greenAbstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
4.2field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 25 citations in OpenAlex.

  1. Review
  2. Molecular detection of fluoroquinolone-resistantFrontiers in cellular and infection microbiology · 2022
    Article
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  4. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Rodrigo AlonsoDepartamento de Inmunología, Microbiología y Parasitología, Facultad de Farmacia, Universidad del País Vasco (UPV-EHU), Vitoria-Gasteiz, Spain. oipfeasa@vc.ehu.es
Estibaliz Mateo
Cecilia Girbau
Estibaliz Churruca
Irati Martinez
Aurora Fernández-Astorga
University of the Basque Country · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A fragment of the gyrA gene was sequenced from 34 isolates of Campylobacter coli, including 23 isolates resistant to ciprofloxacin. All ciprofloxacin-resistant isolates examined by DNA sequencing carried a point mutation at position Thr-86 on the gyrA gene product, involving the replacement of Thr-86 by Ile. A combined PCR-restriction fragment length polymorphism technique using RsaI was developed to detect this mutation.

Indexed as

AnimalsAnimals, DomesticAnti-Bacterial AgentsCampylobacter coliCiprofloxacinDNA, BacterialDNA GyraseDNA PrimersDrug Resistance, BacterialFluoroquinolonesHumansMolecular Sequence DataMutationPolymorphism, Restriction Fragment LengthReverse Transcriptase Polymerase Chain ReactionAnti-Bacterial AgentsCiprofloxacinDNA, BacterialDNA GyraseDNA PrimersFluoroquinolones

Identifiers

PMID15561873
PMCPMC529227
OpenAlexW1992429647

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.