Evidence map›Paper›PMID 15557666›Full record

Trial reportInfection and immunity2004

Acellular pertussis vaccines and complement killing of Bordetella pertussis.

Alison A Weiss, Angela K Patton, Scott H Millen, Swei-Ju Chang, Joel I Ward, David I Bernstein

Abstract readClinical TrialRandomized Controlled Trial
In one paragraph

Trial report in Infection and immunity, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
0.4field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 29 citations in OpenAlex.

  1. Vaccines · 2026
    Review
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  11. Review
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  14. Antibody responses to Bordetella bronchiseptica in vaccinated and infected dogs.The Canadian veterinary journal = La revue veterinaire canadienne · 2014
    Article
  15. Toward a new vaccine for pertussis.Proceedings of the National Academy of Sciences of the United States of America · 2014
    Article
  16. Article
  17. Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Alison A WeissDepartment of Molecular Genetics, Biochemistry, and Microbiology, University of Cincinnati, 231 Albert Sabin Way, Cincinnati, OH 45267-0524, USA. Alison.Weiss@uc.edu
Angela K Patton
Scott H Millen
Swei-Ju Chang
Joel I Ward
David I Bernstein
University of Cincinnati · USCincinnati Children's Hospital Medical Center · USHarbor–UCLA Medical Center · USUCLA Medical Center · US

Funding

EVALUATING NON-AIDS INFECTIOUS DISEASE CONTROL MEASURES-266945252N01AI045252 · NIAID · CHILDREN'S HOSPITAL MED CTR (CINCINNATI) · 1994 to 2003
$1.6M
HUMAN SERUM AND PROTECTION AGAINST BORDETELLA PERTUSSISR01AI045715 · NIAID · UNIVERSITY OF CINCINNATI · PI WEISS, ALISON A. · 2000 to 2004
$1.3M
EVALUATING NON-AIDS INFECTIOUS DISEASE CONTROL MEASURES-266945249N01AI045249 · NIAID · RESEARCH AND EDUCATION INSTITU · 1994 to 2003
$0k
EVALUATION OF CONTROL MEASURES AGAINST DISEASES OTHER THAN AIDS-266025463N01AI025463 · NIAID · HARBOR-UCLA RESEARCH &EDUCATI · PI WARD, JOEL · 2003 to 2006
–
NCI NIH HHS N01 AI025463NIAID NIH HHS N01 AI 25463NIAID NIH HHS N01 AI 2549NIAID NIH HHS N01 AI 45249NIAID NIH HHS N01 AI 45252NIAID NIH HHS R01 AI045715NIAID NIH HHS R01 AI 45715
6 · The paper itself

Abstract

Antibody-dependent complement killing of Bordetella pertussis after immunization with a three-component acellular pertussis vaccine was characterized. Postimmunization activity was unchanged for about half of the adult vaccine recipients. The responses of the other individuals were complex, with evidence of both beneficial and antagonistic responses occurring, sometimes in the same individual.

Indexed as

Antibodies, BacterialBlood Bactericidal ActivityBordetella pertussisComplement System ProteinsDouble-Blind MethodHumansImmunizationImmunoglobulin AImmunoglobulin GPertussis VaccineProspective StudiesVaccines, AcellularAntibodies, BacterialComplement System ProteinsImmunoglobulin AImmunoglobulin GPertussis VaccineVaccines, Acellular

Identifiers

PMID15557666
PMCPMC529164
OpenAlexW2115335781

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.