ArticlePlant physiology2004
Plant-specific microtubule-associated protein SPIRAL2 is required for anisotropic growth in Arabidopsis.
Article in Plant physiology, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 59 papers.
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Who cites it
59 citing papers in PubMed, 133 citations in OpenAlex.
- Fibrous network nature of plant cell walls enables tunable mechanics for development.Nature communications · 2025Article
- Phosphate promotes Arabidopsis root skewing and circumnutation through reorganisation of the microtubule cytoskeleton.The New phytologist · 2024Article
- Spatiotemporally distinct responses to mechanical forces shape the developing seed of Arabidopsis.The EMBO journal · 2024Article
- A divergent tumor overexpressed gene domain and oligomerization contribute to SPIRAL2 function in stabilizing microtubule minus ends.The Plant cell · 2024Article
- Development of a 45K pepper GBTS liquid-phase gene chip and its application in genome-wide association studies.Frontiers in plant science · 2024Article
- Crystal structure of the Arabidopsis SPIRAL2 C-terminal domain reveals a p80-Katanin-like domain.PloS one · 2023Article
- Defects in division plane positioning in the root meristematic zone affect cell organization in the differentiation zone.Journal of cell science · 2022Article
- Characterization of Cry2 genes (CRY2a and CRY2b) of B. napus and comparative analysis of BnCRY1 and BnCRY2a in regulating seedling photomorphogenesis.Plant molecular biology · 2022Article
- Current Understanding of the Genetics and Molecular Mechanisms Regulating Wood Formation in Plants.Genes · 2022Review
- Cell biology of primary cell wall synthesis in plants.The Plant cell · 2022Review
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- Discovery, characterization and functional improvement of kumamonamide as a novel plant growth inhibitor that disturbs plant microtubules.Scientific reports · 2021Article
- A network-based framework for shape analysis enables accurate characterization of leaf epidermal cells.Nature communications · 2021Article
- Cellular requirements for PIN polar cargo clustering in Arabidopsis thaliana.The New phytologist · 2021Article
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- Genetic localization of the SPC gene controlling pod coiling direction in Medicago truncatula.Genes & genomics · 2020Article
- Rice microtubule-associated protein IQ67-DOMAIN14 regulates grain shape by modulating microtubule cytoskeleton dynamics.Plant biotechnology journal · 2020Article
- Comprehensive Sequence Analysis ofGenes · 2020Article
- Transcriptome Analysis ofFrontiers in plant science · 2020Article
Corrections and comments
- Erratum issuedHayashi, Kazuyuki [corrected to Hayashi, Kazunori]
Authors and funding
9 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In diffusely growing plant cells, cortical microtubules play an important role in regulating the direction of cell expansion. Arabidopsis (Arabidopsis thaliana) spiral2 (spr2) mutant is defective in directional cell elongation and exhibits right-handed helical growth in longitudinally expanding organs such as root, hypocotyl, stem, petiole, and petal. The growth of spr2 roots is more sensitive to microtubule-interacting drugs than is wild-type root growth. The SPR2 gene encodes a plant-specific 94-kD protein containing HEAT-repeat motifs that are implicated in protein-protein interaction. When expressed constitutively, SPR2-green fluorescent protein fusion protein complemented the spr2 mutant phenotype and was localized to cortical microtubules as well as other mitotic microtubule arrays in transgenic plants. Recombinant SPR2 protein directly bound to taxol-stabilized microtubules in vitro. Furthermore, SPR2-specific antibody and mass spectrometry identified a tobacco (Nicotiana tabacum) SPR2 homolog in highly purified microtubule-associated protein fractions from tobacco BY-2 cell cultures. These results suggest that SPR2 is a novel microtubule-associated protein and is required for proper microtubule function involved in anisotropic growth.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.