Evidence map›Paper›PMID 15555064›Full record

ArticleHealth and quality of life outcomes2004

Health-related quality of life among adolescents with allergy-like conditions - with emphasis on food hypersensitivity.

Birgitta Marklund, Staffan Ahlstedt, Gun Nordström

Open access · goldAbstract readComparative Study
In one paragraph

Article in Health and quality of life outcomes, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 3 pooled it
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 3 syntheses or guidelines pooled it, 128 citations in OpenAlex.

  1. Pooled it
  2. The Prevalence of Tree Nut Allergy: A Systematic Review.Current allergy and asthma reports · 2015
    Pooled it
  3. Guideline
  4. Prevalence and Clinical Symptoms of Wheat Allergy in Adults and Adolescents in Central Europe.Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology · 2025
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Observational
  12. Article
  13. Quality of life in patients with food allergy.Clinical and molecular allergy : CMA · 2016
    Review
  14. Dietary exclusion for childhood atopic dermatitis.Canadian family physician Medecin de famille canadien · 2015
    Review
  15. Article
  16. Food allergy and quality of life: what have we learned?Current allergy and asthma reports · 2013
    Review
  17. Article
  18. Article
  19. Children and adolescents' health-related quality of life in relation to eczema, asthma and hay fever: results from a population-based cross-sectional study.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2011
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Birgitta MarklundCentre for Allergy Research, Karolinska Institutet, S-171 77 Solna, Sweden. birgitta.marklund@omv.ki.se
Staffan Ahlstedt
Gun Nordström
Karolinska Institutet · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIt is known that there is an increase in the prevalence of allergy and that allergic diseases have a negative impact on individuals' health-related quality of life (HRQL). However, research in this field is mainly focused on individuals with verified allergy, i.e. leaving out those with self-reported allergy-like conditions but with no doctor-diagnosis. Furthermore, studies on food hypersensitivity and quality of life are scarce. In order to receive information about the extent to which adolescent females and males experience allergy-like conditions and the impact of these conditions on their everyday life, the present study aimed to investigate the magnitude of self-reported allergy-like conditions in adolescence and to evaluate their HRQL. Special focus was put on food hypersensitivity as a specific allergy-like condition and on gender differences.

methodsIn connection with lessons completed at the children's school, a study-specific questionnaire and the generic instrument SF-36 were distributed to 1488 adolescents, 13-21 years old (response rate 97%).

resultsSixty-four per cent of the respondents reported some kind of allergy-like condition: 46% reported hypersensitivity to defined substances and 51% reported allergic diseases (i.e. asthma/wheezing, eczema/rash, rhino-conjunctivitis). A total of 19% reported food hypersensitivity. Females more often reported allergy-like conditions compared with males (p < 0.001). The adolescents with allergy-like conditions reported significantly lower HRQL (p < 0.001) in seven of the eight SF-36 health scales compared with adolescents without such conditions, regardless of whether the condition had been doctor-diagnosed or not. Most adolescents suffered from complex allergy-like conditions.

conclusionsThe results indicate a need to consider the psychosocial impact of allergy-like conditions during school age. Further research is needed to elucidate the gender differences in this area. A team approach addressing better understanding of how allergy-like conditions impair the HRQL may improve the management of the adolescent's health problems, both in health-care services and in schools.

Indexed as

Sickness Impact ProfileAdolescentAdultAsthmaConjunctivitisExanthemaFemaleFood HypersensitivityHumansHypersensitivityMaleProspective StudiesQuality of LifeRhinitisRisk FactorsSex Factors

Identifiers

PMID15555064
PMCPMC534793
OpenAlexW2118832804

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.