ReviewMetabolic brain disease2004
Hepatitis C virus-associated extrahepatic manifestations: a review.
Review in Metabolic brain disease, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
31 citing papers in PubMed, 1 synthesis or guideline pooled it, 123 citations in OpenAlex.
- SASLT practice guidelines: management of hepatitis C virus infection.Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association · 2012Guideline
- Hepatitis C Infection Is Not a Cardiovascular Risk Factor in Young Adults.Biomedicines · 2024Article
- Monoclonal Antibodies in the Management of Inflammation in Wound Healing: An Updated Literature Review.Journal of clinical medicine · 2024Review
- HCV Genotype Has No Influence on the Incidence of Diabetes-EpiTer Multicentre Study.Journal of clinical medicine · 2022Article
- Hepatitis C virus: Morphogenesis, infection and therapy.World journal of hepatology · 2018Review
- Evidence for association between hepatitis C virus and Parkinson's disease.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2017Review
- Extra-hepatic infection of hepatitis C virus in the colon tissue and its relationship with hepatitis C virus pathogenesis.Journal of medical microbiology · 2016Article
- Total joint arthroplasty in patients with chronic infectious liver disease.Arthroplasty today · 2016Article
- Myasthenia Crisis Induced by Pegylated-Interferon in Patient With Chronic Hepatitis C: A Case Report.Medicine · 2016Article
- Hepatitis C genotype 4: The past, present, and future.World journal of hepatology · 2015Review
- Dermatologic Extrahepatic Manifestations of Hepatitis C.Journal of clinical and translational hepatology · 2015Review
- Local treatment of non healing leg ulcers in a patient with hepatitis C virus infection.International wound journal · 2015Article
- Cutaneous manifestations of viral hepatitis.Current infectious disease reports · 2015Article
- Study of pruritus in chronic hepatitis C patients.World journal of gastroenterology · 2014Article
- Persistent neurocognitive decline in a clinic sample of hepatitis C virus-infected persons receiving interferon and ribavirin treatment.Journal of neurovirology · 2014Article
- [Comorbidity of rheumatic and hepatic diseases].Zeitschrift fur Rheumatologie · 2013Article
- Measuring the response of extrahepatic symptoms and quality of life to antiviral treatment in patients with hepatitis C.Hepatitis research and treatment · 2013Article
- Efficacy and safety of rituximab in the treatment of vasculitic leg ulcers associated with hepatitis C virus infection.Case reports in rheumatology · 2012Article
- Morphologic features of extrahepatic manifestations of hepatitis C virus infection.Clinical & developmental immunology · 2012Review
- HCV synergizes with body weight in the promotion of insulin resistance.Journal of viral hepatitis · 2011Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The hepatitis C virus (HCV) infection is a worldwide disease that is characterized by a preferential chronic evolution with mild to severe liver disease, including cirrhosis and, in lesser proportion, hepatocarcinoma. Out of these complications, HCV is frequently reported to complicate extrahepatic manifestations. Among those associated to HCV infection with a high degree of certainty, mixed cryoglobulinemia and its complications (skin, neurological, renal, rheumatological involvement) are the most prevalent (50%) in HCV-infected patients. The other diseases include noncryoglobulinemic systemic vasculitis, splenic lymphoma with villous lymphocytes, fatigue, porphyria cutanea tarda, sicca syndrome, and autoantibodies production. The extrahepatic manifestations that share mild-degree certainty of association with HCV infection include B-cell non-Hodgkin lymphoma, autoimmune thrombocytopenia, pruritus, and type II diabetes mellitus. The other diseases such as autoimmune thyroiditis, lichen planus are more questionable for their eventual association with HCV and others (pulmonary fibrosis with or without polymyositis, progressive encephalomyelitis, Mooren's corneal ulcers, erythema nodosum, chronic polyradiculonevritis) are mostly case reports. Howerver, even in cases of tight association, the mechanisms through which HCV may promote or induce extrahepatic manifestations remain unclear and merit further investigations.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.