Evidence map›Paper›PMID 15554160›Full record

ArticleLipids2004

Successful utilization of lyophilized lipoprotein(a) as a biological reagent.

Angelo M Scanu, Janet Hinman, Ditta Pfaffinger, Celina Edelstein

Abstract read
PubMed Publisher
In one paragraph

Article in Lipids, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Lipoprotein (a): a historical appraisal.Journal of lipid research · 2017
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Angelo M ScanuDepartments of Medicine and Biochemistry and Molecular Biology, University of Chicago, Chicago, Illinois 60637, USA. ascanu@medicine.bsd.uchicago.edu
Janet Hinman
Ditta Pfaffinger
Celina Edelstein

Funding

Plasmapheresis for Lp(a)R01HL063209 · NHLBI · UNIVERSITY OF CHICAGO · PI SCANU, ANGELO M · 2001 to 2009
$3.2M
INTERACTIONS OF LP(A) WITH VASCULAR EXTRACELLULAR MATRIXR01HL063115 · NHLBI · UNIVERSITY OF CHICAGO · PI SCANU, ANGELO M · 1999 to 2002
$876k
LIPOPROTEIN (A) STANDARDIZATION PROGRAMN01HV088175 · HV · UNIVERSITY OF WASHINGTON · PI MARCOVINA, SANTICA M · 1998 to 2000
$261k
NHLBI NIH HHS HL63115NHLBI NIH HHS HL63209NHLBI NIH HHS N01 HV88175
6 · The paper itself

Abstract

Lipoprotein(a) [Lp(a)] represents a class of lipoprotein particles having as a protein moiety apoB-100 linked by a single disulfide bond to apolipoprotein(a) [apo(a)], a multikringle structure with a high degree of homology with plasminogen. A recognized feature of Lp(a) is its instability on storage caused by attendant protein and lipid modifications that affect the structural, functional, and immunological properties of this lipoprotein. Here we present data showing that, under appropriate conditions of cryopreservation, Lp(a) retains the properties of the freshly isolated product, and we provide examples supporting the stability of this cryopreserved product as a primary standard in immunoassay settings and in cell culture systems.

Indexed as

CryopreservationDrug StabilityFreeze DryingIndicators and ReagentsLipoprotein(a)MethodsReference StandardsIndicators and ReagentsLipoprotein(a)

Identifiers

PMID15554160

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.