Trial reportEuropean journal of nuclear medicine and molecular imaging2005
FDG-PET is able to detect pancreatic carcinoma in chronic pancreatitis.
Trial report in European journal of nuclear medicine and molecular imaging, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 2 of them syntheses that pooled it.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 2 syntheses or guidelines pooled it, 102 citations in OpenAlex.
- Imaging modalities for characterising focal pancreatic lesions.The Cochrane database of systematic reviews · 2017Pooled it
- FDG-PET in diagnosis, staging and prognosis of pancreatic carcinoma: a meta-analysis.World journal of gastroenterology · 2013Pooled it
- Overview of F18-FDG uptake patterns in retroperitoneal pathologies: imaging findings, pitfalls, and artifacts.Abdominal radiology (New York) · 2024Review
- Follicular pancreatitis: A rare pancreatic inflammatory pseudotumor.Clinical imaging · 2020Review
- Increased 18F-FDG uptake of heterotopic pancreatitis in the small intestine: A CARE-compliant case report.Medicine · 2016Article
- Quantification of tumour (18) F-FDG uptake: Normalise to blood glucose or scale to liver uptake?European radiology · 2015Article
- Utility of PET/CT in diagnosis, staging, assessment of resectability and metabolic response of pancreatic cancer.World journal of gastroenterology · 2014Review
- The role ofJournal of radiation oncology · 2013Article
- Multimodality imaging of pancreatic ductal adenocarcinoma: a review of the literature.HPB : the official journal of the International Hepato Pancreato Biliary Association · 2012Review
- Preoperative 18[F]-fluorodeoxyglucose positron emission tomography/computed tomography predicts early recurrence after pancreatic cancer resection.International journal of clinical oncology · 2011Article
- PET imaging of inflammation and adenocarcinoma xenografts using vascular adhesion protein 1 targeting peptide 68Ga-DOTAVAP-P1: comparison with 18F-FDG.European journal of nuclear medicine and molecular imaging · 2010Article
- Incidence and characteristics of chronic and lymphoplasmacytic sclerosing pancreatitis in patients scheduled to undergo a pancreatoduodenectomy.HPB : the official journal of the International Hepato Pancreato Biliary Association · 2010Article
- [PET and PET-CT of malignant tumors of the exocrine pancreas].Der Radiologe · 2009Review
- Article
- Initial evaluation of 18F-fluorothymidine (FLT) PET/CT scanning for primary pancreatic cancer.European journal of nuclear medicine and molecular imaging · 2008Article
- Differentiation of autoimmune pancreatitis from suspected pancreatic cancer by fluorine-18 fluorodeoxyglucose positron emission tomography.Journal of gastroenterology · 2008Article
- Pancreatic carcinoma coexisting with chronic pancreatitis versus tumor-forming pancreatitis: diagnostic utility of the time-signal intensity curve from dynamic contrast-enhanced MR imaging.World journal of gastroenterology · 2007Article
- State-of-the-art PET/CT of the pancreas: current role and emerging indications.Radiographics : a review publication of the Radiological Society of North America, IncArticle
- Imaging in chronic pancreatitis: State of the art review.The Indian journal of radiology & imagingArticle
Corrections and comments
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Authors and funding
6 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purpose2-(18F)-fluoro-2-deoxy-D-glucose positron emission tomography (FDG-PET) is an imaging technique which enables detection of malignancies. FDG-PET has been established as a tool for the diagnosis of pancreatic carcinoma (CA). Early detection is mandatory as cure can only be achieved in non-advanced disease. This is, however, very difficult with conventional radiological techniques. Patients with chronic pancreatitis (CP) are at risk of developing CA. A simple, reliable screening method for malignant degeneration is highly desirable. We set out to investigate whether FDG-PET is able to detect CA in the setting of CP and can fulfil a potential role in the early detection of CA in CP.
methodsFDG-PET was performed in 77 CP patients and in six patients with CP complicated by CA (CP + CA). We included 26 CA patients as a positive control. A positive scan was defined as focal FDG accumulation in the pancreas region.
resultsIn 67 of the 77 CP (87%) patients, pancreatic FDG accumulation was absent. Six patients had significant accumulation. In CA, 24/26 patients had a positive PET. Five out of the six patients with CP + CA had focal uptake, while minor uptake was seen in one patient. FDG-PET was positive in almost all CA patients and CP + CA patients. FDG-PET was negative in the large majority (87%) of CP patients, which suggests that a positive PET scan in CP patients must lead to efforts to exclude a malignancy.
conclusionThese data suggest that FDG-PET has a potential role as a diagnostic tool for detecting CA in longstanding CP.
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