Evidence map›Paper›PMID 15548858›Full record

ReviewJournal of muscle research and cell motility2004

Cell migration and metastasis as targets of small RNA-based molecular genetic analyses.

Eigo Suyama, Hiroaki Kawasaki, Renu Wadhwa, Kazunari Taira

Abstract readReview
PubMed Publisher
In one paragraph

Review in Journal of muscle research and cell motility, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Eigo SuyamaDepartment of Chemistry and Biotechnology, School of Engineering, The University of Tokyo, Tokyo, Japan.
Hiroaki Kawasaki
Renu Wadhwa
Kazunari Taira

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Metastatic tumor cells can migrate from one place to another in the body. This involves their adherence to host cell layers and subsequent transcellular movements by a complex process, molecular basis of which are yet to be clarified. Elucidation of genes functionally involved in metastasis may lead to deeper understanding of the mechanism of cell migration, and identification and designing of metastasis-modulating strategies for cancer therapeutics. We review here cell migration in tumor metastasis and the use of small RNA-based approaches to identify functional genes. We then describe our promising novel approach that uses randomized ribozyme libraries for identification of genes involved in cell migration, a consistent feature of metastatic cells.

Indexed as

AnimalsCell AdhesionCell MovementChemotaxisGene Expression Regulation, NeoplasticHumansNeoplasm InvasivenessNeoplastic Cells, CirculatingRNA, CatalyticRNA, Small InterferingTumor Cells, CulturedRNA, CatalyticRNA, Small Interfering

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.