Evidence map›Paper›PMID 15545991›Full record

ArticleThe Journal of clinical investigation2004

What determines glomerular capillary permeability?

William M Deen

Abstract readComment
In one paragraph

Article in The Journal of clinical investigation, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
45citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

45 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Acute kidney injury in patients with burns.Nature reviews. Nephrology · 2024
    Review
  6. Article
  7. Review
  8. Article
  9. Urinary immunoglobulins in viral diagnosis: An overview.The Indian journal of medical research · 2022
    Review
  10. Article
  11. Low doses of folic acid can reduce hyperhomocysteinemia-induced glomerular injury in spontaneously hypertensive rats.Hypertension research : official journal of the Japanese Society of Hypertension · 2020
    Article
  12. Article
  13. Article
  14. Review
  15. RSC advances · 2019
    Article
  16. Review
  17. Review
  18. Basement Membranes in Development and Disease.Current topics in developmental biology · 2018
    Review
  19. Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

1 author.

William M DeenDepartment of Chemical Engineering, Division of Biological Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, USA. wmdeen@mit.edu

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

There have been exciting recent advances in our understanding of the structural and molecular biology of the glomerular slit diaphragm, as described in a report in this issue of the JCI. These findings, combined with data on the permeability of the basement membrane and evidence that the endothelium may be a more important barrier than often supposed, are allowing a clearer understanding to emerge of how the 3 parts of the glomerular capillary wall jointly determine its functional properties.

Indexed as

Capillary PermeabilityAnimalsBasement MembraneCapillariesEndothelium, VascularEpithelial CellsHumansKidney GlomerulusMembrane ProteinsMiceMice, KnockoutModels, BiologicalProteinsMembrane ProteinsnephrinProteins

Identifiers

PMID15545991
PMCPMC525751

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.