ArticleGenome research2004
Coelacanth genome sequence reveals the evolutionary history of vertebrate genes.
Article in Genome research, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 1 of them a synthesis that pooled it.
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Who cites it
33 citing papers in PubMed, 1 synthesis or guideline pooled it.
- The evolutionary conservation of eukaryotic membrane-bound adenylyl cyclase isoforms.Frontiers in pharmacology · 2022Pooled it
- Parallel Evolution of Ameloblastic scpp Genes in Bony and Cartilaginous Vertebrates.Molecular biology and evolution · 2022Article
- Genome and Phylogenetic Analysis of Genes Involved in the Immune System ofFrontiers in genetics · 2019Article
- Article
- Regulation of neural circuit formation by protocadherins.Cellular and molecular life sciences : CMLS · 2017Review
- Characterization of a Single Genomic Locus Encoding the Clustered Protocadherin Receptor Diversity in Xenopus tropicalis.G3 (Bethesda, Md.) · 2016Article
- Evolutionary changes in vertebrate genome signatures with special focus on coelacanth.DNA research : an international journal for rapid publication of reports on genes and genomes · 2014Article
- Expansion of stochastic expression repertoire by tandem duplication in mouse Protocadherin-α cluster.Scientific reports · 2014Article
- Genomic organisation of the seven ParaHox genes of coelacanths.Journal of experimental zoology. Part B, Molecular and developmental evolution · 2014Article
- Interspecies insertion polymorphism analysis reveals recent activity of transposable elements in extant coelacanths.PloS one · 2014Article
- Coelacanth genomes reveal signatures for evolutionary transition from water to land.Genome research · 2013Article
- Analysis of the transcriptome of the Indonesian coelacanth Latimeria menadoensis.BMC genomics · 2013Article
- Article
- Theria-specific homeodomain and cis-regulatory element evolution of the Dlx3-4 bigene cluster in 12 different mammalian species.Journal of experimental zoology. Part B, Molecular and developmental evolution · 2012Article
- Profiling of gene duplication patterns of sequenced teleost genomes: evidence for rapid lineage-specific genome expansion mediated by recent tandem duplications.BMC genomics · 2012Article
- A living fossil in the genome of a living fossil: Harbinger transposons in the coelacanth genome.Molecular biology and evolution · 2012Article
- Molecular codes for neuronal individuality and cell assembly in the brain.Frontiers in molecular neuroscience · 2012Article
- An endogenous foamy-like viral element in the coelacanth genome.PLoS pathogens · 2012Article
- Conservation of shh cis-regulatory architecture of the coelacanth is consistent with its ancestral phylogenetic position.EvoDevo · 2010Article
- Two lamprey Hedgehog genes share non-coding regulatory sequences and expression patterns with gnathostome Hedgehogs.PloS one · 2010Article
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The coelacanth is one of the nearest living relatives of tetrapods. However, a teleost species such as zebrafish or Fugu is typically used as the outgroup in current tetrapod comparative sequence analyses. Such studies are complicated by the fact that teleost genomes have undergone a whole-genome duplication event, as well as individual gene-duplication events. Here, we demonstrate the value of coelacanth genome sequence by complete sequencing and analysis of the protocadherin gene cluster of the Indonesian coelacanth, Latimeria menadoensis. We found that coelacanth has 49 protocadherin cluster genes organized in the same three ordered subclusters, alpha, beta, and gamma, as the 54 protocadherin cluster genes in human. In contrast, whole-genome and tandem duplications have generated two zebrafish protocadherin clusters comprised of at least 97 genes. Additionally, zebrafish protocadherins are far more prone to homogenizing gene conversion events than coelacanth protocadherins, suggesting that recombination- and duplication-driven plasticity may be a feature of teleost genomes. Our results indicate that coelacanth provides the ideal outgroup sequence against which tetrapod genomes can be measured. We therefore present L. menadoensis as a candidate for whole-genome sequencing.
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