ArticlePlant physiology2004
Organization of monoterpene biosynthesis in Mentha. Immunocytochemical localizations of geranyl diphosphate synthase, limonene-6-hydroxylase, isopiperitenol dehydrogenase, and pulegone reductase.
Article in Plant physiology, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 54 papers.
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54 citing papers in PubMed, 179 citations in OpenAlex.
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- Exploring the co-operativity of secretory structures for defense and pollination in flowering plants.Planta · 2024Review
- Metabolic engineering of terpene metabolism in lavender.Beni-Suef University journal of basic and applied sciences · 2024Review
- Histochemical Analysis and Ultrastructure of Trichomes and Laticifers ofPlants (Basel, Switzerland) · 2023Article
- Glandular trichome specificity of menthol biosynthesis pathway gene promoters from Mentha × piperita.Planta · 2022Article
- Unraveling the Biosynthesis of Carvacrol in Different Tissues ofInternational journal of molecular sciences · 2022Article
- Characterisation of the Mentha canadensis R2R3-MYB transcription factor gene McMIXTA and its involvement in peltate glandular trichome development.BMC plant biology · 2022Article
- Genetic Manipulation of Biosynthetic Pathways in Mint.Frontiers in plant science · 2022Review
- The biosynthesis of thymol, carvacrol, and thymohydroquinone in Lamiaceae proceeds via cytochrome P450s and a short-chain dehydrogenase.Proceedings of the National Academy of Sciences of the United States of America · 2021Article
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- Anti-Hyperalgesic Properties of Menthol and Pulegone.Frontiers in pharmacology · 2021Article
- Genome sequencing of four culinary herbs reveals terpenoid genes underlying chemodiversity in the Nepetoideae.DNA research : an international journal for rapid publication of reports on genes and genomes · 2020Article
- Identifying and engineering the ideal microbial terpenoid production host.Applied microbiology and biotechnology · 2019Review
- Glandular trichomes of the leaves in three Doronicum species (Senecioneae, Asteraceae): morphology, histochemistry, and ultrastructure.Protoplasma · 2019Article
- Ultrastructure and secretion of glandular trichomes in species of subtribe Cajaninae Benth (Leguminosae, Phaseoleae).Protoplasma · 2019Article
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2 authors at 1 institution in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
We present immunocytochemical localizations of four enzymes involved in p-menthane monoterpene biosynthesis in mint: the large and small subunits of peppermint (Mentha x piperita) geranyl diphosphate synthase, spearmint (Mentha spicata) (-)-(4S)-limonene-6-hydroxylase, peppermint (-)-trans-isopiperitenol dehydrogenase, and peppermint (+)-pulegone reductase. All were localized to the secretory cells of peltate glandular trichomes with abundant labeling corresponding to the secretory phase of gland development. Immunogold labeling of geranyl diphosphate synthase occurred within secretory cell leucoplasts, (-)-4S-limonene-6-hydroxylase labeling was associated with gland cell endoplasmic reticulum, (-)-trans-isopiperitenol dehydrogenase labeling was restricted to secretory cell mitochondria, while (+)-pulegone reductase labeling occurred only in secretory cell cytoplasm. We discuss this pathway compartmentalization in relation to possible mechanisms for the intracellular movement of monoterpene metabolites, and for monoterpene secretion into the extracellular essential oil storage cavity.
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