ArticleProceedings. Biological sciences2004
Modelling strategies for controlling SARS outbreaks.
Article in Proceedings. Biological sciences, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 119 papers, 3 of them syntheses that pooled it.
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Who cites it
119 citing papers in PubMed, 3 syntheses or guidelines pooled it, 404 citations in OpenAlex.
- Quarantine alone or in combination with other public health measures to control COVID-19: a rapid review.The Cochrane database of systematic reviews · 2020Pooled it
- Estimate of the Basic Reproduction Number for COVID-19: A Systematic Review and Meta-analysis.Journal of preventive medicine and public health = Yebang Uihakhoe chi · 2020Pooled it
- Quarantine alone or in combination with other public health measures to control COVID-19: a rapid review.The Cochrane database of systematic reviews · 2020Pooled it
- Survey on mathematical modeling of infectious disease dynamics: insights and applications.BMC infectious diseases · 2026Review
- Modeling and Simulation of the Role of Mass Testing in Controlling COVID-19.Bulletin of mathematical biology · 2026Article
- The Emergence of Turing Instability and Pattern Formation in a Nonlinear Stochastic Spatiotemporal Epidemic Model with Reinfections.Acta biotheoretica · 2026Article
- Hybrid modeling and forecasting of COVID-19: integrating SEAIQHRD and GPR for improved predictions.BMC infectious diseases · 2026Article
- A discrete SIR epidemic model incorporating media impact, resource limitaions and threshold switching strategies.Infectious Disease Modelling · 2025Article
- Modelling behavioural changes and vaccination in the transmission of respiratory viruses with co-infection.Journal of mathematical biology · 2025Article
- Canada's provincial COVID-19 pandemic modelling efforts: A review of mathematical models and their impacts on the responses.Canadian journal of public health = Revue canadienne de sante publique · 2024Review
- Bayesian inference for the onset time and epidemiological characteristics of emerging infectious diseases.Frontiers in public health · 2024Article
- Mapping immunological and host receptor binding determinants of SARS-CoV spike protein utilizing the Qubevirus platform.The Journal of biological chemistry · 2023Article
- Assessing potential insights of an imperfect testing strategy: Parameter estimation and practical identifiability using early COVID-19 data in India.Communications in nonlinear science & numerical simulation · 2023Article
- Multi-source dynamic ensemble prediction of infectious disease and application in COVID-19 case.Journal of thoracic disease · 2023Article
- A mathematical model for COVID-19 considering waning immunity, vaccination and control measures.Scientific reports · 2023Article
- Filter Masks during the Second Phase of SARS-CoV-2: Study on Population.International journal of environmental research and public health · 2023Article
- Qualitative analysis of a fractional-order two-strain epidemic model with vaccination and general non-monotonic incidence rate.International journal of dynamics and control · 2022Article
- To study the transmission dynamic of SARS-CoV-2 using nonlinear saturated incidence rate.Physica A · 2022Article
- Article
- Mathematical modelling of the epidemiology of COVID-19 infection in Ghana.Scientific African · 2022Article
59 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors at 10 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Severe acute respiratory syndrome (SARS), a new, highly contagious, viral disease, emerged in China late in 2002 and quickly spread to 32 countries and regions causing in excess of 774 deaths and 8098 infections worldwide. In the absence of a rapid diagnostic test, therapy or vaccine, isolation of individuals diagnosed with SARS and quarantine of individuals feared exposed to SARS virus were used to control the spread of infection. We examine mathematically the impact of isolation and quarantine on the control of SARS during the outbreaks in Toronto, Hong Kong, Singapore and Beijing using a deterministic model that closely mimics the data for cumulative infected cases and SARS-related deaths in the first three regions but not in Beijing until mid-April, when China started to report data more accurately. The results reveal that achieving a reduction in the contact rate between susceptible and diseased individuals by isolating the latter is a critically important strategy that can control SARS outbreaks with or without quarantine. An optimal isolation programme entails timely implementation under stringent hygienic precautions defined by a critical threshold value. Values below this threshold lead to control, but those above are associated with the incidence of new community outbreaks or nosocomial infections, a known cause for the spread of SARS in each region. Allocation of resources to implement optimal isolation is more effective than to implement sub-optimal isolation and quarantine together. A community-wide eradication of SARS is feasible if optimal isolation is combined with a highly effective screening programme at the points of entry.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.