ArticleLeukemia2005
Mutations in the BRAF and N-ras genes in childhood acute lymphoblastic leukaemia.
Article in Leukemia, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 44 citations in OpenAlex.
- Review
- An updated account on molecular heterogeneity of acute leukemia.American journal of blood research · 2021Review
- Review
- Review
- BRAF kinase domain mutations are present in a subset of chronic myelomonocytic leukemia with wild-type RAS.American journal of hematology · 2014Article
- RAS mutations in early age leukaemia modulated by NQO1 rs1800566 (C609T) are associated with second-hand smoking exposures.BMC cancer · 2014Article
- Ras/Raf/MEK/ERK Pathway Activation in Childhood Acute Lymphoblastic Leukemia and Its Therapeutic Targeting.Frontiers in oncology · 2014Review
- Hematopoietic expression of oncogenic BRAF promotes aberrant growth of monocyte-lineage cells resistant to PLX4720.Molecular cancer research : MCR · 2013Article
- Thyroid carcinoma-associated genetic mutations also occur in thyroid lymphomas.Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc · 2012Article
- Mutations and deregulation of Ras/Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR cascades which alter therapy response.Oncotarget · 2012Review
- Oncogene mutation profiling of pediatric solid tumors reveals significant subsets of embryonal rhabdomyosarcoma and neuroblastoma with mutated genes in growth signaling pathways.Clinical cancer research : an official journal of the American Association for Cancer Research · 2012Article
- Roles of the Ras/Raf/MEK/ERK pathway in leukemia therapy.Leukemia · 2011Review
- BRAF mutations in hairy-cell leukemia.The New England journal of medicine · 2011Article
- Initial testing (stage 1) of the multi-targeted kinase inhibitor sorafenib by the pediatric preclinical testing program.Pediatric blood & cancer · 2010Article
- Initial testing (stage 1) of AZD6244 (ARRY-142886) by the Pediatric Preclinical Testing Program.Pediatric blood & cancer · 2010Article
- Mutations in the c-Kit gene disrupt mitogen-activated protein kinase signaling during tumor development in adenoid cystic carcinoma of the salivary glands.Neoplasia (New York, N.Y.) · 2010Article
- BRAF mutations are very rare in B- and T-cell pediatric acute lymphoblastic leukemias.Leukemia · 2008Article
- Selective Raf inhibition in cancer therapy.Expert opinion on therapeutic targets · 2007Review
- The T1790A BRAF mutation (L597Q) in childhood acute lymphoblastic leukemia is a functional oncogene.Leukemia · 2007Article
Corrections and comments
- Commented on by
Authors and funding
6 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
PubMed holds no abstract for this paper.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.