ReviewJournal of biological rhythms2004
Finding new clock components: past and future.
Review in Journal of biological rhythms, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 51 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
51 citing papers in PubMed.
- Elucidation of daily timed-palatable meal-anticipatory activity in the circadian system of mice.American journal of physiology. Gastrointestinal and liver physiology · 2026Article
- Exogenous Melatonin as a Sleep-promoting Agent beyond its Chronobiotic Properties: A Scoping Review of its Effects on Key Sleep-wake Neurotransmitters.Current neuropharmacology · 2026Article
- Orexin-A and Circadian Disruption in Alzheimer's Disease: Implications for Amyloid-Beta Pathology.Molecular neurobiology · 2025Article
- A novel circadian behavior rhythm in arrhythmiciScience · 2025Article
- The Relationship between Circadian Rhythm and Cancer Disease.International journal of molecular sciences · 2024Review
- Melatonin as a Chronobiotic with Sleep-promoting Properties.Current neuropharmacology · 2023Review
- Precision caffeine therapy for apnea of prematurity and circadian rhythms: New possibilities open up.Frontiers in pharmacology · 2022Review
- Autonomous clocks that regulate organelle biogenesis, cytoskeletal organization, and intracellular dynamics.eLife · 2021Review
- The 50th anniversary of the Konopka and Benzer 1971 paper in PNAS: "Clock Mutants ofProceedings of the National Academy of Sciences of the United States of America · 2021Article
- Light Pollution and Cancer.International journal of molecular sciences · 2020Review
- Tuning the circadian period of cyanobacteria up to 6.6 days by the single amino acid substitutions in KaiC.Proceedings of the National Academy of Sciences of the United States of America · 2020Article
- Structural insights into melatonin receptors.The FEBS journal · 2020Review
- The Impact of Time of Day on Energy Expenditure: Implications for Long-Term Energy Balance.Nutrients · 2019Review
- Nuclear receptor HNF4A transrepresses CLOCK:BMAL1 and modulates tissue-specific circadian networks.Proceedings of the National Academy of Sciences of the United States of America · 2018Article
- Development of the Astyanax mexicanus circadian clock and non-visual light responses.Developmental biology · 2018Article
- A brief review about melatonin, a pineal hormone.Archives of endocrinology and metabolism · 2018Review
- mTOR signaling regulates central and peripheral circadian clock function.PLoS genetics · 2018Article
- Active State Organization of Spontaneous Behavioral Patterns.Scientific reports · 2018Article
- Transcriptional architecture of the mammalian circadian clock.Nature reviews. Genetics · 2017Review
- Of Fighting Flies, Mice, and Men: Are Some of the Molecular and Neuronal Mechanisms of Aggression Universal in the Animal Kingdom?PLoS genetics · 2015Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
Abstract
The molecular mechanism of circadian clocks has been unraveled primarily by the use of phenotype-driven (forward) genetic analysis in a number of model systems. We are now in a position to consider what constitutes a clock component, whether we can establish criteria for clock components, and whether we have found most of the primary clock components. This perspective discusses clock genes and how genetics, molecular biology, and biochemistry have been used to find clock genes in the past and how they will be used in the future.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.