Evidence map›Paper›PMID 15534037›Full record

ReviewThe Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry2004

Plasticity in the olfactory system: lessons for the neurobiology of memory.

D A Wilson, A R Best, R M Sullivan

2 registry-linked trialsOpen access · greenAbstract readReview
In one paragraph

Review in The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 57 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
57citing papers in PubMed, 3 pooled it
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05216614 phase2withdrawnnot on this mapstarted 2021, after this paper: background citation

Fluvoxamine to Augment Olfactory Recovery For Long COVID-19 Parosmia (FluCOP Trial)

TypeinterventionalSponsorWashington University School of MedicineRan2021 to 2022Enrolled0ConditionsCOVID-19, Olfactory Disorder, ParosmiaArmsFluvoxamine, Placebo
NCT05947643 phase2completednot on this mapstarted 2022, after this paper: background citation

Smell in COVID-19 and Efficacy of Nasal Theophylline 3

TypeinterventionalSponsorWashington University School of MedicineRan2022 to 2025Enrolled77ConditionsCOVID-19Armstheophylline, Placebo
3 · Its place in the literature

Who cites it

57 citing papers in PubMed, 3 syntheses or guidelines pooled it, 188 citations in OpenAlex.

  1. The efficacy of olfactory training in improving olfactory function: a meta-analysis.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2024
    Pooled it
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  6. Smell Is Emotion.Brain sciences · 2025
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  8. Representational drift and learning-induced stabilization in the piriform cortex.Proceedings of the National Academy of Sciences of the United States of America · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

D A WilsonDepartment of Zoology, University of Oklahoma, Norman, OK 73019, USA. dwilson@ou.edu
A R Best
R M Sullivan
University of Oklahoma · US

Funding

Neurobiology of Cognitive Functioning in InfancyR01HD033402 · NICHD · UNIVERSITY OF OKLAHOMA NORMAN · PI SULLIVAN, REGINA MARIE · 1995 to 2006
$1.3M
NICHD NIH HHS R01 HD033402
6 · The paper itself

Abstract

We are rapidly advancing toward an understanding of the molecular events underlying odor transduction, mechanisms of spatiotemporal central odor processing, and neural correlates of olfactory perception and cognition. A thread running through each of these broad components that define olfaction appears to be their dynamic nature. How odors are processed, at both the behavioral and neural level, is heavily dependent on past experience, current environmental context, and internal state. The neural plasticity that allows this dynamic processing is expressed nearly ubiquitously in the olfactory pathway, from olfactory receptor neurons to the higher-order cortex, and includes mechanisms ranging from changes in membrane excitability to changes in synaptic efficacy to neurogenesis and apoptosis. This review will describe recent findings regarding plasticity in the mammalian olfactory system that are believed to have general relevance for understanding the neurobiology of memory.

Indexed as

AnimalsBrainHumansMemoryModels, NeurologicalNeuronal PlasticityOlfactory PathwaysReceptors, NeurotransmitterSmellSynaptic TransmissionReceptors, Neurotransmitter

Identifiers

PMID15534037
PMCPMC1868530
OpenAlexW2081919343

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.