ArticleJournal of clinical microbiology2004
Stochastic transmission of multiple genotypically distinct Anaplasma marginale strains in a herd with high prevalence of Anaplasma infection.
Article in Journal of clinical microbiology, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 30 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
30 citing papers in PubMed.
- Molecular Prevalence and Genetic Diversity Based onLife (Basel, Switzerland) · 2023Article
- Temporal Dynamics ofMicroorganisms · 2023Article
- Satisfactory breeding potential is transiently eliminated in beef bulls with clinical anaplasmosis.BMC veterinary research · 2022Article
- Both Coinfection and Superinfection Drive Complex Anaplasma marginale Strain Structure in a Natural Transmission Setting.Infection and immunity · 2021Article
- Ecological and evolutionary perspectives on tick-borne pathogen co-infections.Current research in parasitology & vector-borne diseases · 2021Review
- Quantitative analysis of Anaplasma marginale acquisition and transmission by Dermacentor andersoni fed in vitro.Scientific reports · 2020Article
- Dynamics of repeat-associated plasticity in theGene: X · 2019Article
- Detection and Characterisation of Anaplasma marginale and A. centrale in South Africa.Veterinary sciences · 2018Review
- Co-infections with multiple genotypes of Anaplasma marginale in cattle indicate pathogen diversity.Parasites & vectors · 2018Article
- Article
- Insight into the genetic diversity of Anaplasma marginale in cattle from ten provinces of China.Parasites & vectors · 2017Article
- Article
- Superinfection Exclusion of the Ruminant Pathogen Anaplasma marginale in Its Tick Vector Is Dependent on the Time between Exposures to the Strains.Applied and environmental microbiology · 2016Article
- Antigenic Variation in Bacterial Pathogens.Microbiology spectrum · 2016Article
- Anaplasma marginale: Diversity, Virulence, and Vaccine Landscape through a Genomics Approach.BioMed research international · 2016Review
- Anaplasma marginale and Anaplasma phagocytophilum: Rickettsiales pathogens of veterinary and public health significance.Parasitology research · 2015Review
- Anaplasma marginale superinfection attributable to pathogen strains with distinct genomic backgrounds.Infection and immunity · 2014Article
- High genetic diversity of Anaplasma marginale detected from Philippine cattle.The Journal of veterinary medical science · 2014Article
- Antigenic variation and transmission fitness as drivers of bacterial strain structure.Cellular microbiology · 2013Review
- Borrelia hermsii acquisition order in superinfected ticks determines transmission efficiency.Infection and immunity · 2013Article
Corrections and comments
- Erratum issued
Authors and funding
7 authors.
Funding
Abstract
Multiple genotypically unique strains of the tick-borne pathogen Anaplasma marginale occur and are transmitted within regions where the organism is endemic. In this study, we tested the hypothesis that specific A. marginale strains are preferentially transmitted. The study herd of cattle (n = 261) had an infection prevalence of 29% as determined by competitive inhibition enzyme-linked immunosorbent assay and PCR, with complete concordance between results of the two assays. Genotyping revealed the presence of 11 unique strains within the herd. Although the majority of the individuals (70 of 75) were infected with only a single A. marginale strain, five animals each carried two strains with markedly distinct genotypes, indicating that superinfection does occur with distinct A. marginale strains, as has been reported with A. marginale and A. marginale subsp. centrale strains. Identification of strains in animals born into and infected within the herd during the period from 1998 to 2003 revealed no significant difference from the overall strain prevalence in the herd, results that do not support the occurrence of preferential strain transmission within a population of persistently infected animals and are most consistent with pathogen strain transmission being stochastic.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.