Evidence map›Paper›PMID 15528688›Full record

ArticleJournal of clinical microbiology2004

Detection and selection of microsatellites in the genome of Paracoccidioides brasiliensis as molecular markers for clinical and epidemiological studies.

Erika Nascimento, Roberto Martinez, André Rodrigues Lopes, Luciano Angelo de Souza Bernardes, Carolina Pomponio Barco, Maria Helena S Goldman, John W Taylor, Juan G McEwen, Marina Pasetto Nobrega, Francisco G Nobrega and 1 more

Open access · greenAbstract read
In one paragraph

Article in Journal of clinical microbiology, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.6field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 35 citations in OpenAlex.

  1. Article
  2. Molecular Tools for Detection and Identification ofJournal of fungi (Basel, Switzerland) · 2020
    Review
  3. Species boundaries in the human pathogen Paracoccidioides.Fungal genetics and biology : FG & B · 2017
    Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 3 countries.

Erika NascimentoDepartamento de Ciências Farmacêuticas de Ribeirão Preto, Universidade de São Paulo, Brazil.
Roberto Martinez
André Rodrigues Lopes
Luciano Angelo de Souza Bernardes
Carolina Pomponio Barco
Maria Helena S Goldman
John W Taylor
Juan G McEwen
Marina Pasetto Nobrega
Francisco G Nobrega
Gustavo H Goldman
Universidade do Vale do Paraíba · BRFundação Faculdade de Medicina · BRUniversidad de Antioquia · COUniversidade de São Paulo · BRUniversity of California, Berkeley · US

Funding

PARACOCCIDIOIDOMYCOSIS--EVOLUTION AND STRAIN-TYPINGR03TW001308 · FIC · UNIVERSITY OF CALIFORNIA BERKELEY · PI TAYLOR, JOHN W. · 2000 to 2002
$121k
FIC NIH HHS R03TW001308
6 · The paper itself

Abstract

Paracoccidioides brasiliensis, a thermodimorphic fungus, is the causative agent of the prevalent systemic mycosis in Latin America, paracoccidioidomycosis (PCM). Here, we describe the microsatellite patterns observed in a collection of P. brasiliensis random sequence tags. We identified 1,117 microsatellite patterns in about 3.8 Mb of unique sequences (0.47% of the total DNA used in the analysis). The majority of these microsatellites (87.5%) are found in noncoding sequences. We used two polymorphic microsatellites located on noncoding and coding sequences, as well as two microsatellites located on introns, as molecular markers to discriminate P. brasiliensis isolates, to look for relationships between the genetic background of the strains and the types of human disease they cause. We did not observe any correlation between the clinical form of human PCM and four simple sequence repeat patterns analyzed.

Indexed as

Genetic MarkersAnimalsArmadillosGenome, FungalHumansMicrosatellite RepeatsParacoccidioidesParacoccidioidomycosisPhylogenyPolymerase Chain ReactionVirulenceGenetic Markers

Identifiers

PMID15528688
PMCPMC525212
OpenAlexW2132748675

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.