ArticleApplied and environmental microbiology2004
Seasonal shedding of multiple Cryptosporidium genotypes in California ground squirrels (Spermophilus beecheyi).
Article in Applied and environmental microbiology, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
16 citing papers in PubMed, 41 citations in OpenAlex.
- Molecular Characterization and Zoonotic Potential ofTransboundary and emerging diseases · 2026Article
- Investigation of Cryptosporidium infection in a broad range of hosts in northern China.Parasites & vectors · 2025Article
- Genotyping and subtyping of Cryptosporidium spp. and Giardia duodenalis isolates from two wild rodent species in Gansu Province, China.Scientific reports · 2022Article
- Diverse Genotypes and Species ofMicroorganisms · 2021Article
- Prevalence and Genotypes of Cryptosporidium in Wildlife Populations Co-Located in a Protected Watershed in the Pacific Northwest, 2013 to 2016.Microorganisms · 2020Article
- Public health significance of zoonoticInternational journal for parasitology. Parasites and wildlife · 2016Review
- Cryptosporidium rubeyi n. sp. (Apicomplexa: Cryptosporidiidae) in multiple Spermophilus ground squirrel species.International journal for parasitology. Parasites and wildlife · 2015Article
- Elevation and vegetation determine Cryptosporidium oocyst shedding by yellow-bellied marmots (Marmota flaviventris) in the Sierra Nevada Mountains.International journal for parasitology. Parasites and wildlife · 2015Article
- Prevalence, environmental loading, and molecular characterization of Cryptosporidium and Giardia isolates from domestic and wild animals along the Central California Coast.Applied and environmental microbiology · 2012Article
- Multiple unique Cryptosporidium isolates from three species of ground squirrels (Spermophilus beecheyi, S. beldingi, and S. lateralis) in California.Applied and environmental microbiology · 2010Article
- Cryptosporidium spp. in wild, laboratory, and pet rodents in china: prevalence and molecular characterization.Applied and environmental microbiology · 2009Article
- 90-kilodalton heat shock protein, Hsp90, as a target for genotyping Cryptosporidium spp. known to infect humans.Eukaryotic cell · 2009Article
- Prevalence and genetic characterization of Cryptosporidium isolates from common brushtail possums (Trichosurus vulpecula) adapted to urban settings.Applied and environmental microbiology · 2008Article
- Cryptosporidium genotypes in wildlife from a new york watershed.Applied and environmental microbiology · 2007Article
- Capture and retention of Cryptosporidium parvum oocysts by Pseudomonas aeruginosa biofilms.Applied and environmental microbiology · 2006Article
- Deposition of Cryptosporidium oocysts in streambeds.Applied and environmental microbiology · 2006Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Twelve percent of 853 California ground squirrels (Spermophilus beecheyi) from six different geographic locations in Kern County, Calif., were found to be shedding on average 44,482 oocysts g of feces(-1). The mean annual environmental loading rate of Cryptosporidium oocysts was 57,882 oocysts squirrel(-1) day(-1), with seasonal patterns of fecal shedding ranging from <10,000 oocysts squirrel(-1) day(-1) in fall, winter, and spring to levels of 2 x 10(5) oocysts squirrel(-1) day(-1) in summer. Juveniles were about twice as likely as adult squirrels to be infected and shed higher concentrations of oocysts than adults did, with particularly high levels of infection and shedding being found among juvenile male squirrels. Based on DNA sequencing of a portion of the 18S small-subunit rRNA gene, there existed three genotypes of Cryptosporidium species in these populations of squirrels (Sbey03a, Sbey03b, and Sbey03c; accession numbers AY462231 to AY462233, respectively). These unique DNA sequences were most closely related (96 to 97% homology) to porcine C. parvum (AF115377) and C. wrairi (AF115378). Inoculating BALB/c neonatal mice with up to 10,000 Sbey03b or Sbey03c fresh oocysts from different infected hosts did not produce detectable levels of infection, suggesting that this common genotype shed by California ground squirrels is not infectious for mice and may constitute a new species of Cryptosporidium.
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