ReviewEcotoxicology (London, England)2004
Experimental designs to assess endocrine disrupting effects in invertebrates. A review.
Review in Ecotoxicology (London, England), 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
7 citing papers in PubMed, 1 synthesis or guideline pooled it, 76 citations in OpenAlex.
- The Chronic Effects of Copper and Cadmium on Life History Traits Across Cladocera Species: A Meta-analysis.Archives of environmental contamination and toxicology · 2019Pooled it
- Assessing Environmental Risks during the Drug Development Process for Parasitic Vector-Borne Diseases: A Critical Reflection.ACS infectious diseases · 2024Review
- Microplastics in the aquatic and terrestrial environment: sources (with a specific focus on personal care products), fate and effects.Environmental sciences Europe · 2016Review
- Developmental toxicity of endocrine disrupters bisphenol A and vinclozolin in a terrestrial isopod.Archives of environmental contamination and toxicology · 2010Article
- Small is useful in endocrine disrupter assessment--four key recommendations for aquatic invertebrate research.Ecotoxicology (London, England) · 2007Article
- Endocrine disruption in prosobranch molluscs: evidence and ecological relevance.Ecotoxicology (London, England) · 2007Review
- Towards an internationally harmonized test method for reproductive and developmental effects of endocrine disrupters in marine copepods.Ecotoxicology (London, England) · 2007Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In order to gain basic understanding of the ecological effects of vertebrate Endocrine Disrupting Chemicals (EDCs), many research groups are currently testing these chemicals using aquatic invertebrates. Small crustaceans, such as cladocerans and copepods, are of particular interest since they are ecologically important and their short life cycles allow obtaining information on demographic parameters. Despite the existence of diverse literature on the development, growth and reproductive effects of EDCs on these crustaceans, only a few studies have unambiguously assessed a truly endocrine disrupting effect. This review discusses new experimental designs to differentiate between endocrine disruption and other causes of reproductive and developmental impairment. Our findings clearly illustrate that many studies may have falsely concluded that chemicals have endocrine disrupting modes of action when in fact a much simpler explanation was not previously ruled out (e.g., egg mortality, feeding inhibition). This means that there is an urgent need for integration of toxic effects on energy intake to toxicity assessments. Such an approach would permit different ectotoxicological models of action, including endocrine disrupting effects, to be distinguished and their relative roles in the overall toxic response to be clarified.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.