ArticleDevelopment genes and evolution2005
Ci-POU-IV expression identifies PNS neurons in embryos and larvae of the ascidian Ciona intestinalis.
Article in Development genes and evolution, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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15 citing papers in PubMed.
- A gene regulatory network for specification and morphogenesis of a Mauthner Cell homolog in non-vertebrate chordates.Developmental biology · 2025Article
- Lhx3/4 initiates a cardiopharyngeal-specific transcriptional program in response to widespread FGF signaling.PLoS biology · 2024Article
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- Highly distinct genetic programs for peripheral nervous system formation in chordates.BMC biology · 2022Article
- Neuronal identities derived by misexpression of the POU IV sensory determinant in a protovertebrate.Proceedings of the National Academy of Sciences of the United States of America · 2022Article
- Conservation of peripheral nervous system formation mechanisms in divergent ascidian embryos.eLife · 2020Article
- Exploring miR-9 Involvement inInternational journal of molecular sciences · 2020Article
- Neuronal identity: the neuron types of a simple chordate sibling, the tadpole larva of Ciona intestinalis.Current opinion in neurobiology · 2019Review
- Efficient genome editing using CRISPR-Cas-mediated homology directed repair in the ascidian Ciona robusta.Genesis (New York, N.Y. : 2000) · 2018Article
- Bioadhesion in ascidians: a developmental and functional genomics perspective.Interface focus · 2015Review
- POU genes are expressed during the formation of individual ganglia of the cephalopod central nervous system.EvoDevo · 2014Article
- Expression of AmphiPOU-IV in the developing neural tube and epidermal sensory neural precursors in amphioxus supports a conserved role of class IV POU genes in the sensory cells development.Development genes and evolution · 2006Article
- Formation of the ascidian epidermal sensory neurons: insights into the origin of the chordate peripheral nervous system.PLoS biology · 2006Article
- Cataloging transcription factor and major signaling molecule genes for functional genomic studies in Ciona intestinalis.Development genes and evolution · 2005Article
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Authors and funding
8 authors.
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No grant is acknowledged in the PubMed record.
Abstract
Several lines of evidence suggest that members of the POU domain gene family may regulate invertebrate and vertebrate neurogenesis. In particular, POU IV genes appear to be neural genes involved in differentiation of sensory neurons, as demonstrated in mollusc, Drosophila, Caenorhabditis elegans and vertebrates. In the present work, we describe the developmental expression of a homologue of POU IV genes, Ci-POU-IV, in the ascidian Ciona intestinalis. Ci-POU-IV is expressed in the precursor cells of the neural system during development and in the neural system of the larva. In particular, transcripts are prevalent in the peripheral nervous system (PNS), with expression in the central nervous system (CNS) restricted to the posterior sensory vesicle. Therefore, the evolution of a complex sensory system seems to be under the control of a common genetic mechanism.
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