ReviewWorld journal of surgery2004
Current strategies for surgical management and adjuvant treatment of childhood papillary thyroid carcinoma.
Review in World journal of surgery, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 2 syntheses or guidelines pooled it, 112 citations in OpenAlex.
- Predictive factors for recurrence of differentiated thyroid cancer in patients under 21 years of age and a meta-analysis of the current literature.Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine · 2016Pooled it
- Management Guidelines for Children with Thyroid Nodules and Differentiated Thyroid Cancer.Thyroid : official journal of the American Thyroid Association · 2015Guideline
- Thyroid surgery in children: a single pediatric center experience.Updates in surgery · 2026Article
- Navigating the transition: assessing continuity and loss in endocrinology care.Endocrine connections · 2025Article
- Concurrent Association of Multifocality, Bilaterality, and Recurrence in Pediatric Papillary Thyroid Cancer Patients.Yonsei medical journal · 2025Article
- Clinical characteristics and prognosis of histological subtypes of papillary thyroid carcinoma in pediatric patients.Endocrine oncology (Bristol, England) · 2025Article
- Risk factors of postoperative hypoparathyroidism after total thyroidectomy in pediatric patients with thyroid cancer.Annals of pediatric endocrinology & metabolism · 2023Article
- Perioperative outcomes of thyroid cancer surgery in children and adults: a nationwide inpatient database study in Japan.Annals of clinical epidemiology · 2023Article
- Outcome and complications after surgery for thyroid carcinoma in pediatric age-an evaluation of practice.World journal of surgical oncology · 2022Article
- Radiofrequency Ablation for Cervical Metastatic Lymph Nodes in Children and Adolescents With Papillary Thyroid Carcinoma: A Preliminary Study.Frontiers in endocrinology · 2021Article
- Cervical Lymph Node Metastases of Papillary Thyroid Carcinoma, in the Central and Lateral Compartments, in Children and Adolescents: Predictive Factors.World journal of surgery · 2018Article
- Pediatric papillary thyroid carcinoma: outcomes and survival predictors in 2504 surgical patients.Pediatric surgery international · 2016Article
- Papillary Thyroid Cancer in a Child with Progressive Transformation of Germinal Centers.Case reports in otolaryngology · 2016Article
- Papillary Thyroid Carcinoma in Children and Adolescents: Long-Term Follow-Up and Clinical Characteristics.World journal of surgery · 2015Article
- Minimally invasive follicular thyroid cancer (MIFTC)--a consensus report of the European Society of Endocrine Surgeons (ESES).Langenbeck's archives of surgery · 2014Article
- Differentiated thyroid carcinoma: comparison of histopathologic characteristics, clinical course, and outcome between young children and adolescents.Medical oncology (Northwood, London, England) · 2013Article
- Differentiated thyroid carcinoma of children and adolescents: 27-year experience in the yonsei university health system.Journal of Korean medical science · 2013Article
- Pediatric thyroid disease: when is surgery necessary, and who should be operating on our children?Journal of clinical research in pediatric endocrinology · 2013Review
- Pediatric thyroid cancers: an Indian perspective.Indian journal of surgical oncology · 2012Article
- The treatment of differentiated thyroid cancer in children: emphasis on surgical approach and radioactive iodine therapy.Endocrine reviews · 2011Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Childhood papillary thyroid carcinoma is associated with more locally aggressive and more frequent distant disease than its adult counterpart. Recurrence rates tend to be higher in children, but cause-specific mortality remains low. Optimal initial treatment of childhood papillary thyroid carcinoma should include total or near-total thyroidectomy and central compartment node clearance. Modified neck dissections should be performed for biopsy-proven lateral neck disease. Every effort should be made to maintain parathyroid and laryngeal nerve function. Radical neck dissections are to be avoided. Radioiodine remnant ablation (RRA), appropriate thyroid hormone suppressive therapy (THST), and judicious use of therapeutic doses of (131)I are applied to achieve a disease-free status, which is most often confirmed by negative neck ultrasonography, negative whole-body scan (either withdrawal or recombinant human thyroid-stimulating hormone-stimulated), and extremely low levels of serum thyroglobulin. Appropriate utilization of (131)I, THST, repeat surgery, external beam radiotherapy, and rarely chemotherapy may provide long-term palliation and some cures in patients with recurrent/persistent disease. Follow-up should be lifelong, and the care of children after age 17 should subsequently be transferred to adult-care endocrinologists with expertise in managing thyroid neoplasia. Optimal surgical management can be achieved if adequate operations are routinely carried out by "high-volume" thyroid surgeons with expertise in the care of children. Nowhere is a multidisciplinary approach (endocrinologists, surgeons, nuclear medicine physicians, pediatricians, pathologists, oncologists) more critical than in the long-term management of papillary thyroid carcinoma that presents during childhood.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.